Primary Biliary Cholangitis (PBC) Diagnostic Panel

Primary Biliary Cholangitis (PBC) Diagnostic Panel

Test Code

19876
86015, 86038, 86235 (x2), 86381, 86376 (x2)
19876
86015, 86038, 86235 (x2), 86381, 86376 (x2)
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Primary Biliary Cholangitis (PBC) Diagnostic Panel -

This panel may be helpful in the diagnostic evaluation of individuals with suspected primary biliary cholangitis (PBC). This panel includes anti-mitochondrial antibody (AMA), with reflex to titer; an antinuclear antibody (ANA) immunofluorescence assay (IFA) screen, performed on human epithelial type 2 (HEp-2) cells, with reflex to titer and pattern; actin (smooth muscle) antibody (SMA; IgG); Sjogren antibodies (SSA, SSB); thyroid peroxidase (TPO) antibody; and liver kidney microsome type 1 (LKM-1) antibody (IgG).

PBC can be diagnosed by fulfilling 2 of the 3 diagnostic criteria that comprise ...

Test Resources

None found for this test
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Test Details

Includes

  • ANA Screen, IFA, with Reflex to Titer and Pattern
  • Sjögren's Antibodies (SS-A, SS-B)
  • Mitochondrial Antibody with Reflex to Titer
  • Actin (Smooth Muscle) Antibody (IgG)
  • Thyroid Peroxidase Antibody (Anti-TPO)
  • Liver Kidney Microsome (LKM-1) Antibody (IgG)
  •  
  • If ANA Screen, IFA is positive, then ANA Titer and Pattern will be performed at an additional charge (CPT code(s): 86039).
  • If Mitochondrial Antibody Screen is positive, then Mitochondrial Antibody Titer will be performed at an additional charge (CPT code(s): 86381).

Methodology

Immunoassay (IA)

Reference Range(s)

See individual tests

Alternative Name(s)

Primary Biliary Cirrhosis Panel

LOINC® Codes, Performing Laboratory

Service Area must be determined
ANA Screen, IFA, with Reflex to Titer and Pattern
Sjögren's Antibodies (SS-A, SS-B)
Mitochondrial Antibody with Reflex to Titer
Actin (Smooth Muscle) Antibody (IgG)
Thyroid Peroxidase Antibody (Anti-TPO)
Liver Kidney Microsome (LKM-1) Antibody (IgG)

If ANA Screen, IFA is positive, then ANA Titer and Pattern will be performed at an additional charge (CPT code(s): 86039).
If Mitochondrial Antibody Screen is positive, then Mitochondrial Antibody Titer will be performed at an additional charge (CPT code(s): 86381).

Methodology

Immunoassay (IA)

Reference Range(s)

See individual tests

Alternative Name(s)

Primary Biliary Cirrhosis Panel
Service Area must be determined

Preferred Specimen(s)

4.5 mL serum

Minimum Volume

1.6 mL

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 4 days
  • Refrigerated: 7 days
  • Frozen: 28 days

Reject Criteria

Hemolysis • Lipemia • Grossly icteric

Setup Schedule

Service Area must be determined
4.5 mL serum
1.6 mL
Transport tube
Refrigerated (cold packs)
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 28 days
Hemolysis • Lipemia • Grossly icteric
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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