von Willebrand Disease Panel without Collagen Binding Assay (CBA)
Test code
CPT code(s)*
Clinical significance
Test resources
Test FAQ
Details
Includes
Partial Thromboplastin Time, Activated
Factor VIII Activity, Clotting
Ristocetin Cofactor
von Willebrand Factor Antigen
von Willebrand Antigen Multimeric Analysis
Methodology
See individual tests
Assay category
von Willebrand Antigen, Multimeric Analysis: This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Alternative name(s)
vWF,VWD
Specimen requirements | |
|---|---|
| Patient preparation | None Specified |
| Preferred specimen(s) | 1 mL (x4) frozen platelet-poor plasma collected in 3.2% sodium citrate (light blue-top) tubes |
| Minimum volume | 0.75 mL (x4) |
| Collection instructions | Please submit a separate, frozen vial for each special coagulation assay ordered. Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice. Note: Storage of whole blood at refrigerated temperatures prior to processing may lead to cryoprecipitate formation and falsely low Factor ViII and von Willebrand Factor studies. |
| Transport container | Transport tube(s) |
| Transport temperature | Frozen |
| Specimen stability | Room temperature: Unacceptable Refrigerated: Unacceptable Frozen: 14 days |
| Reject criteria | Received room temperature • Received refrigerated |
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.
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