Lupus Anticoagulant and Antiphospholipid Confirmation (on Coumadin®) with Consultation
Test Code
Clinical Significance
Lupus Anticoagulant and Antiphospholipid Confirmation (on Coumadin®) with Consultation
Test Resources
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Test Details
Thrombin Clotting Time
Cardiolipin Antibodies (IgG, IgM)
Beta-2-Glycoprotein I Antibodies (IgG, IgM)
Hexagonal Phase Confirmation
dRVVT Screen with Reflex to dRVVT Confirm and dRVVT 1:1 Mix
Coagulation Consultation
If dRVVT Screen is prolonged (>45 seconds), then dRVVT Confirm will be performed at an additional charge (CPT code(s): 85597).
If dRVVT Confirm is positive, then dRVVT 1:1 Mixing Study will be performed at an additional charge (CPT code(s): 85613).
Methodology
Reference Range(s)
Preferred Specimen(s)
1 mL frozen platelet-poor plasma collected in each of six 3.2% sodium citrate (light blue-top) tubes
Minimum Volume
0.5 mL (x6)
Collection Instructions
Please submit a separate, frozen vial for each special coagulation assay ordered. Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice.
Transport Container
Transport tube(s)
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 14 days
Reject Criteria
Hemolysis • Received room temperature • Received refrigerated
Setup Schedule
Refrigerated: Unacceptable
Frozen: 14 days