Lupus Anticoagulant and Antiphospholipid Confirmation (on Coumadin®)

Lupus Anticoagulant and Antiphospholipid Confirmation (on Coumadin®)

Test Code

19672
85598, 85610, 85613, 85670, 86146 (x2), 86147 (x2)
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
19672
85598, 85610, 85613, 85670, 86146 (x2), 86147 (x2)
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano | Quest Nichols Institute -San Juan Capistrano, CA. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Lupus Anticoagulant and Antiphospholipid Confirmation (on Coumadin®)

Test Resources

None found for this test
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Test Details

Includes

  • Prothrombin Time with INR
    Thrombin Clotting Time
    Cardiolipin Antibodies (IgG, IgM)
    Beta-2-Glycoprotein I Antibodies (IgG, IgM)
    Hexagonal Phase Confirmation
    dRVVT Screen with Reflex to dRVVT Confirm and dRVVT 1:1 Mix

    If dRVVT Screen is prolonged (>45 seconds), then dRVVT Confirm will be performed at an additional charge (CPT code(s): 85597).
    If dRVVT Confirm is positive, then dRVVT 1:1 Mixing Study will be performed at an additional charge (CPT code(s): 85613).

Methodology

Clot Detection • Clotting Assay • Immunoassay (IA) • Photo/Optical

Reference Range(s)

See Laboratory Report

LOINC® Codes, Performing Laboratory

Service Area must be determined
Prothrombin Time with INR
Thrombin Clotting Time
Cardiolipin Antibodies (IgG, IgM)
Beta-2-Glycoprotein I Antibodies (IgG, IgM)
Hexagonal Phase Confirmation
dRVVT Screen with Reflex to dRVVT Confirm and dRVVT 1:1 Mix

If dRVVT Screen is prolonged (>45 seconds), then dRVVT Confirm will be performed at an additional charge (CPT code(s): 85597).
If dRVVT Confirm is positive, then dRVVT 1:1 Mixing Study will be performed at an additional charge (CPT code(s): 85613).

Methodology

Clot Detection • Clotting Assay • Immunoassay (IA) • Photo/Optical

Reference Range(s)

See Laboratory Report
Service Area must be determined

Preferred Specimen(s)

1 mL frozen platelet-poor plasma collected in each of six 3.2% sodium citrate (light blue-top) tubes

Minimum Volume

0.5 mL (x6)

Collection Instructions

Please submit a separate, frozen vial for each special coagulation assay ordered.
Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice.

Transport Container

Transport tube(s)

Transport Temperature

Frozen

Specimen Stability

  • Room temperature: Unacceptable
  • Refrigerated: Unacceptable
  • Frozen: 14 days

Reject Criteria

Hemolysis • Received room temperature • Received refrigerated

Setup Schedule

Service Area must be determined
1 mL frozen platelet-poor plasma collected in each of six 3.2% sodium citrate (light blue-top) tubes
0.5 mL (x6)
Please submit a separate, frozen vial for each special coagulation assay ordered.
Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice.
Transport tube(s)
Frozen
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 14 days
Hemolysis • Received room temperature • Received refrigerated
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano | Quest Nichols Institute -San Juan Capistrano, CA. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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