Lipid Panel with Ratios

Lipid Panel with Ratios

Test Code

19543
80061
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
19543
80061
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Not offered in Quest Nichols Institute - Chantilly, VA | Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Lipid Panel with Ratios - This panel measures serum cholesterol and triglyceride (TG) levels. It includes evaluation of the LDL/HDL ratio (calculated), cholesterol/HDL-C ratio (calculated), HDL-C, LDL-C (calculated), non-HDL-C (calculated), total cholesterol, and TG. Comprehensive lipid assessment aids in evaluating cardiovascular disease (CVD) risk and the likelihood of an ischemic event. It is also useful for the prevention and management of atherosclerotic disease and diagnosis of metabolic syndrome [1].

CVD is the leading cause of death in the United States. Individuals with high LDL-C and TG levels are at elevated ...

Test Resources

Test FAQ

LDL Cholesterol Calculations

Test Summary

LDL Cholesterol

Test Details

Includes

  • Cholesterol, Total
    HDL Cholesterol
    Triglycerides
    LDL-Cholesterol (calculated)
    Cholesterol/HDL Ratio (calculated)
    LDL/HDL Ratio (calculated)
    Non-HDL Cholesterol (calculated)

Patient Preparation

If a cholesterol measurement is to be performed along with triglycerides, but not part of a lipid panel, then the patient should be fasting 9-12 hours prior to collection. If the cholesterol is ordered as part of a lipid panel, then a fasting sample is not required.

The assay manufacturer Beckman Coulter advises: N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been determined to interfere with assays for cholesterol and uric acid where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.

Methodology

Spectrophotometry (SP)

Reference Range(s)


Total Cholesterol 		Male
(mg/dL) 		Female
(mg/dL)
<20 Years <170 <170
≥20 Years <200 <200
HDL Cholesterol    
<20 Years >45 >45
≥20 Years ≥40 ≥50
Triglycerides    
≤9 Years <75 <75
10-19 Years <90 <90
≥20 Years <150 <150
LDL-Cholesterol (Calc)    
<20 Years <110 <110
≥20 Years <100 <100
Cholesterol/HDL Ratio (Calc) <5.0 <5.0
LDL/HDL Ratio (Calc)  
Below Average Risk <2.28 <2.34
Average Risk 2.29-4.90 2.35-4.12
Moderate Risk 4.91-7.12 4.13-5.56
High Risk >7.13 >5.57
Non-HDL Cholesterol    
<20 Years <120 <120
≥20 Years <130 <130

LOINC® Codes, Performing Laboratory

Service Area must be determined
Cholesterol, Total
HDL Cholesterol
Triglycerides
LDL-Cholesterol (calculated)
Cholesterol/HDL Ratio (calculated)
LDL/HDL Ratio (calculated)
Non-HDL Cholesterol (calculated)
If a cholesterol measurement is to be performed along with triglycerides, but not part of a lipid panel, then the patient should be fasting 9-12 hours prior to collection. If the cholesterol is ordered as part of a lipid panel, then a fasting sample is not required.

The assay manufacturer Beckman Coulter advises: N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been determined to interfere with assays for cholesterol and uric acid where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.

Methodology

Spectrophotometry (SP)

Reference Range(s)


Total Cholesterol 		Male
(mg/dL) 		Female
(mg/dL)
<20 Years <170 <170
≥20 Years <200 <200
HDL Cholesterol    
<20 Years >45 >45
≥20 Years ≥40 ≥50
Triglycerides    
≤9 Years <75 <75
10-19 Years <90 <90
≥20 Years <150 <150
LDL-Cholesterol (Calc)    
<20 Years <110 <110
≥20 Years <100 <100
Cholesterol/HDL Ratio (Calc) <5.0 <5.0
LDL/HDL Ratio (Calc)  
Below Average Risk <2.28 <2.34
Average Risk 2.29-4.90 2.35-4.12
Moderate Risk 4.91-7.12 4.13-5.56
High Risk >7.13 >5.57
Non-HDL Cholesterol    
<20 Years <120 <120
≥20 Years <130 <130
Service Area must be determined

Preferred Specimen(s)

1 mL serum

Alternative Specimen(s)

Plasma collected in a: Sodium heparin (green-top) tube or lithium heparin (green-top) tube

Minimum Volume

0.5 mL

Collection Instructions

Centrifuge within 30-60 minutes following collection

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Serum
  • Room temperature: 48 hours
  • Refrigerated: 7 days
  • Frozen: 28 days
  •  
  • Plasma
  • Room temperature: 48 hours
  • Refrigerated: 48 hours
  • Frozen: 28 days

Reject Criteria

Gross hemolysis • Moderate to gross icterus • Anticoagulants other than heparin • Received frozen

Setup Schedule

Service Area must be determined
1 mL serum
Plasma collected in a: Sodium heparin (green-top) tube or lithium heparin (green-top) tube
0.5 mL
Centrifuge within 30-60 minutes following collection
Transport tube
Room temperature
Serum
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 28 days

Plasma
Room temperature: 48 hours
Refrigerated: 48 hours
Frozen: 28 days
Gross hemolysis • Moderate to gross icterus • Anticoagulants other than heparin • Received frozen
Service Area must be determined
Not offered in Quest Nichols Institute - Chantilly, VA | Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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