Creatinine Clearance without Glomerular Filtration Rate, Estimated (eGFR)
Test Code
Clinical Significance
Creatinine Clearance without Glomerular Filtration Rate, Estimated (eGFR) - Creatinine Clearance is used to evaluate the glomerular filtration rate (GFR). Clearance is defined as that volume of plasma from which a measured amount of substance could be completely eliminated into the urine per unit of time. Daily creatinine production is fairly constant except when there is massive injury to muscle.
Test Resources
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Test Details
Methodology
Reference Range(s)
| Age | Male (mg/dL) | Female (mg/dL) |
| ≤2 days | 0.79-1.58 | 0.79-1.58 |
| 3-27 days | 0.35-1.23 | 0.35-1.23 |
| 1 month-9 years | 0.20-0.73 | 0.20-0.73 |
| 10-12 years | 0.30-0.78 | 0.30-0.78 |
| 13-15 years | 0.40-1.05 | 0.40-1.00 |
| 16-17 years | 0.60-1.20 | 0.50-1.00 |
| 18-29 years | 0.60-1.24 | 0.50-0.96 |
| 30-39 years | 0.60-1.26 | 0.50-0.97 |
| 40-49 years | 0.60-1.29 | 0.50-0.99 |
| 50-59 years | 0.70-1.30 | 0.50-1.03 |
| 60-69 years | 0.70-1.35 | 0.50-1.05 |
| 70-79 years | 0.70-1.28 | 0.60-1.00 |
| ≥80 years | 0.70-1.22 | 0.60-0.95 |
Creatinine, 24-Hour Urine
| <3 Years | Not established |
| 3-8 Years | 0.10-0.80 g/24 h |
| 9-12 Years | 0.20-1.40 g/24 h |
| 13-17 Years | 0.40-1.90 g/24 h |
| >17 Years | 0.50-2.15 g/24 h |
Urine Creatinine Clearance
| Male | 85-125 mL/minute |
| Female | 75-115 mL/minute |
Preferred Specimen(s)
10 mL aliquot from a well-mixed 24-hour urine collection - no preservative
and 1 mL serum
Minimum Volume
0.5 mL urine • 0.5 serum
Collection Instructions
Record total volume and collection time on specimen container and requisition. Indicate the patient's height and weight on the test requisition.
Note: A serum creatinine level must be collected within 24 hours of the beginning or ending of the urine collection.
Transport Container
Urine: Plastic urine container
Serum: Transport tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 7 days
- Frozen: 28 days
Reject Criteria
Grossly icteric
Setup Schedule
and 1 mL serum
Note: A serum creatinine level must be collected within 24 hours of the beginning or ending of the urine collection.
Serum: Transport tube
Refrigerated: 7 days
Frozen: 28 days