PSA, Total with Reflex to PSA, Free

Test Code

17569

CPT Code(s)

84153

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Test Code

17569

CPT Code(s)

84153

CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

PSA, Total with Reflex to PSA, Free - In men over 50 years with Total PSA between 4.0 and 10.0 ng/mL, the percent (%) Free PSA gives an estimate of the probability of cancer. In these circumstances the measurement of the % Free PSA may aid in avoiding unnecessary biopsies.
Elevated levels of prostate specific antigen (PSA) have been associated with benign and malignant prostatic disorders. Studies indicate that in men 50 years or older measurement of PSA is a useful addition to the digital rectal exam in the early detection of prostate cancer. In addition, PSA decreases to undetectable levels following complete resection of ...

Test Resources

Test FAQ

STRENSIQ® (Asfotase Alfa) Assay Interference

Test Details

Includes

If Total PSA is between 4.0-10.0 ng/mL, then Free PSA will be performed at an additional charge (CPT code(s): 84154).

Methodology

Immunoassay (IA)

Reference Range(s)

PSA, Total

Male	≤4.0 ng/mL
Female	Not established

LOINC® Codes, Performing Laboratory

Service Area must be determined

Includes

If Total PSA is between 4.0-10.0 ng/mL, then Free PSA will be performed at an additional charge (CPT code(s): 84154).

Methodology

Immunoassay (IA)

Reference Range(s)

PSA, Total

Male	≤4.0 ng/mL
Female	Not established

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

2 mL frozen serum

Minimum Volume

0.6 mL

Collection Instructions

Do not collect specimen after a transrectal biopsy, results may be falsely elevated.

Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.

Transport Container

Transport tube

Transport Temperature

Frozen • Room temperature acceptable if received within 72 hours

Specimen Stability

Room temperature: 72 hours
Refrigerated: 72 hours
Frozen: 5 months

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

2 mL frozen serum

Minimum Volume

0.6 mL

Collection Instructions

Transport Container

Transport tube

Transport Temperature

Frozen • Room temperature acceptable if received within 72 hours

Specimen Stability

Room temperature: 72 hours
Refrigerated: 72 hours
Frozen: 5 months

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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