Protein S Activity with Reflex to Protein S Antigen, Total and Free

Test Code

17494

CPT Code(s)

85306

Test Code

17494

CPT Code(s)

85306

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Protein S Activity with Reflex to Protein S Antigen, Total and Free

Test Resources

None found for this test
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Test Details

Includes

If Protein S Activity is <60% for females or <70% for males, then Protein S Antigen Total and Free will be performed at an additional charge (CPT code(s): 85305, 85306).

Methodology

Clot Detection • Immunotrubidimetric

Reference Range(s)

Protein S Activity

Males	70-150	%normal
Female	60-140	%normal

LOINC® Codes, Performing Laboratory

Service Area must be determined

Includes

If Protein S Activity is <60% for females or <70% for males, then Protein S Antigen Total and Free will be performed at an additional charge (CPT code(s): 85305, 85306).

Methodology

Clot Detection • Immunotrubidimetric

Reference Range(s)

Protein S Activity

Males	70-150	%normal
Female	60-140	%normal

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

2 mL frozen plasma collected in a 3.2% sodium citrate (light blue-top) tube [1 mL x 2]

Minimum Volume

1 mL

Collection Instructions

Draw blood in 3.2% sodium citrate ( light blue-top) tubes, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipett, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into new plastic screw-cap vial(s). Freeze immediately and transport on dry ice.

Transport Container

Transport tube(s)

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days

Reject Criteria

Hemolysis

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

2 mL frozen plasma collected in a 3.2% sodium citrate (light blue-top) tube [1 mL x 2]

Minimum Volume

1 mL

Collection Instructions

Transport Container

Transport tube(s)

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days

Reject Criteria

Hemolysis

Setup Schedule

Service Area must be determined

In-home collection is not available in your area through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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