JC Polyoma Virus DNA, Qualitative Real-Time PCR, Serum or Plasma
Test Code
17220
87798
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Clinical Significance
JC Polyoma Virus DNA, Qualitative Real-Time PCR, Serum or Plasma - JC polyoma virus is the cause of progressive multifocal leukoencephalopathy (PML), a demyelinating neurologic disease of immunosuppressed patients. This test detects JC Polyoma Virus DNA in serum or plasma. Detection of virus in specimens from AIDS and other severely immune compromised patients may indicate disease. Serum antibodies are not helpful in diagnosing PML as antibodies are common in the general population. JCV can also be detected in the urine of 3% of pregnant women, but is not associated with proven disease.
Test Resources
None found for this test
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Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.
Test Details
Methodology
Real-Time Polymerase Chain Reaction
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
Not detected
Alternative Name(s)
JC Virus DNA, QL Real Time PCR,Polyomavirus,JCV Polyoma,JC Polyoma Virus DNA, QL,JC Virus DNA, Qual PCR, Plasma,JC Virus DNA, Qual PCR, Serum,JC Virus Qual PCR
Preferred Specimen(s)
0.7 mL plasma collected in an EDTA (lavender-top), ACD (yellow-top), or PPT (white-top) tube or
0.7 mL serum
Minimum Volume
0.3 mL
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
- Room temperature: 48 hours
- Refrigerated: 7 days
- Frozen: 30 days
Setup Schedule
0.7 mL plasma collected in an EDTA (lavender-top), ACD (yellow-top), or PPT (white-top) tube or
0.7 mL serum
0.7 mL serum
0.3 mL
Transport tube
Frozen
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days