17-Hydroxyprogesterone
Test code
CPT code(s)*
Test resources
Clinical focus
Details
Methodology
Chromatography/Mass Spectrometry
Assay category
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Alternative name(s)
17-Alpha-Hydroxprogesterone,17-OHP,OH-Progesterone
Specimen requirements | |
|---|---|
| Patient preparation | None Specified |
| Preferred specimen(s) | 0.5 mL serum collected in a red-top tube (no gel) |
| Alternative specimen(s) | Plasma collected in: EDTA (royal blue-top) tube, sodium heparin (green-top) tube, lithium heparin (green-top) tube or EDTA (lavender-top) tube |
| Minimum volume | 0.25 mL |
| Collection instructions | Separate serum after clotting. Ship serum refrigerated or frozen. Do not submit glass tubes. |
| Transport container | Transport tube |
| Transport temperature | Refrigerated (cold packs) |
| Specimen stability | Room temperature: 48 hours Refrigerated: 7 days Frozen: 2 years |
| Reject criteria | Gross hemolysis • Serum separator tube (SST) |
Reference Range(s)
Adult Males
| 18-30 years | 32-307 ng/dL |
| 31-40 years | 42-196 ng/dL |
| 41-50 years | 33-195 ng/dL |
| 51-60 years | 37-129 ng/dL |
Adult Females
| Pre-Menopausal Mid Follicular | 23-102 ng/dL |
| Pre-Menopausal Surge | 67-349 ng/dL |
| Pre-Menopausal Mid Luteal | 139-431 ng/dL |
| Postmenopausal Phase | ≤45 ng/dL |
| First Trimester | 78-457 ng/dL |
| Second Trimester | 90-357 ng/dL |
| Third Trimester | 144-578 ng/dL |
Pediatric
| Cord Blood** | 1000-3000 ng/dL |
| Premature Infants** (31-35 weeks) | ≤405 ng/dL |
| Term Infants (12 hrs)** | <460 ng/dL |
| Values decline gradually to prepubertal levels | |
| Male and Female | |
| <30 days | Not established |
| 1-11 months | ≤147 ng/dL |
| 1 year | ≤139 ng/dL |
| 2 years | ≤134 ng/dL |
| 3 years | ≤131 ng/dL |
| 4 years | ≤131 ng/dL |
| 5 years | ≤133 ng/dL |
| 6 years | ≤137 ng/dL |
| 7 years | ≤145 ng/dL |
| 8 years | ≤154 ng/dL |
| 9 years | ≤166 ng/dL |
| 10 years | ≤180 ng/dL |
| 11 years | ≤196 ng/dL |
| 12 years | ≤213 ng/dL |
| 13 years | ≤233 ng/dL |
| 14 years | ≤254 ng/dL |
| 15 years | 19-276 ng/dL |
| 16 years | 23-300 ng/dL |
| 17 years | 26-325 ng/dL |
Tanner Stages**
| II-III Males | 12-130 ng/dL |
| II-III Females | 18-220 ng/dL |
| IV-V Males | 51-190 ng/dL |
| IV-V Females | 36-200 ng/dL |
**Includes data from J Clin Endocrinol Metab.1991;73:674-686; J Clin Endocrinol Metab. 1989; 69:1133-1136; and J Clin Endocrinol Metab. 1994; 78:266-270. Pediatr Res 1988;23:525-529. MedLinePlus (accessed 6/16/14).
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.
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