Dopamine, Random Urine

Dopamine, Random Urine

Test Code

17101
82542
17101
82542
Not offered in Quest Nichols Institute - Chantilly, VA | Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Dopamine, Random Urine - Measurement of dopamine levels in urine or blood in addition to urinary vanillylmandelic acid (VMA) and homovanillic acid (HVA) levels may aid in the biochemical diagnosis and monitoring of neuroblastomas [1]. This test may also be useful in evaluating dopamine-secreting pheochromocytomas and paragangliomas (PPGLs) [2].

Neuroblastomas occur predominantly in children and are the most common malignancy under 1 year old. Neuroblastomas are catecholamine-metabolizing tumors with limited ability to store and secrete catecholamines. Thus, catecholamine metabolites (including VMA and HVA) are more ...

Test Resources

None found for this test
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Test Details

Patient Preparation

It is preferable for the patient to be off medications for three days prior to collection. However, common anti-hypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference.
Patient should avoid alcohol, coffee, tea, tobacco and strenuous exercise prior to collection.

Methodology

Liquid Chromatography/Mass Spectormetry (LC/MS)

Reference Range(s)

PediatricNot Established
Adults40-390 mcg/g creat

LOINC® Codes, Performing Laboratory

Service Area must be determined
It is preferable for the patient to be off medications for three days prior to collection. However, common anti-hypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference.
Patient should avoid alcohol, coffee, tea, tobacco and strenuous exercise prior to collection.

Methodology

Liquid Chromatography/Mass Spectormetry (LC/MS)

Reference Range(s)

PediatricNot Established
Adults40-390 mcg/g creat
Service Area must be determined

Preferred Specimen(s)

1 mL random urine with 6N HCl in a sterile screw-cap container

Alternative Specimen(s)

Unpreserved urine with pH ≤6 and shipped frozen

Minimum Volume

0.7 mL

Collection Instructions

After urine collection, add 0.5-1.0 g/L boric acid (or 6N HCl) to maintain a pH below 3. Urine without preservative is acceptable if pH is below 6 and sample is shipped frozen.

Transport Container

Sterile screw-cap container

Transport Temperature

Frozen

Specimen Stability

  • Preserved urine
    Room temperature: Unacceptable
    Refrigerated: 30 days
    Frozen: 60 days

    Unpreserved urine
    Room temperature: Unacceptable
    Refrigerated: 7 days
    Frozen: 60 days

Setup Schedule

Service Area must be determined
1 mL random urine with 6N HCl in a sterile screw-cap container
Unpreserved urine with pH ≤6 and shipped frozen
0.7 mL
After urine collection, add 0.5-1.0 g/L boric acid (or 6N HCl) to maintain a pH below 3. Urine without preservative is acceptable if pH is below 6 and sample is shipped frozen.
Sterile screw-cap container
Frozen

Preserved urine
Room temperature: Unacceptable
Refrigerated: 30 days
Frozen: 60 days

Unpreserved urine
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 60 days

Service Area must be determined
Not offered in Quest Nichols Institute - Chantilly, VA | Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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