Neurokinin A
Test Code
Clinical Significance
Neurokinin A - Neurokinin A is a ten amino acid putative transmitter synthesized in the neurons it is present in. Neurokinin A is a member of the family called Tachykinins which also include Neurokinin B, Substance P, Physalaemin, and Eledoisin. Neurokinin A shares 6 of 10 peptide homologies with Neurokinin B even though they are produced by different genes. Neurokinin A is also very similar in structure to Substance P and produces some of the same biological actions as Substance P. Neurokinin A is a potent bronchoconstrictor. In the gut, Neurokinin A is produced by the intrinsic enteric nervous system.
Test Resources
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Test Details
Methodology
Reference Range(s)
Preferred Specimen(s)
3 mL frozen plasma collected in a 10 mL InterScience Institute’s (ISI) Z-tube™ Preservative
Alternative Specimen(s)
For tumor/tissue and various fluids (i.e. CSF, peritoneal, synovial, etc.) contact Inter Science for requirements and special handling
Minimum Volume
1 mL
Collection Instructions
Collect 10 mL blood directly into ISI's Z-tube™ Preservative and separate as soon as possible. Freeze plasma immediately after separation. Special Z-tube™ Preservatives are available from Inter Science Institute (ISI).
Note: One Z-tube™ may be shared for up to three tests. After centrifuging tube, aliquot 1mL per test in separate vials, mark with name of test and freeze.
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
- Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 6 months
Reject Criteria
Gross hemolysis • Grossly lipemic • Grossly icteric • Received room temperature • Received refrigerated • Not collected in a Z-tube™
Setup Schedule
Note: One Z-tube™ may be shared for up to three tests. After centrifuging tube, aliquot 1mL per test in separate vials, mark with name of test and freeze.
Refrigerated: Unacceptable
Frozen: 6 months