Calprotectin, Stool

Test Code

16796

CPT Code(s)

83993

Test Code

16796

CPT Code(s)

83993

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Calprotectin, Stool - Calprotectin is a non-specific marker of bowel inflammation. Subsequent to white blood cell migration into the intestine, this neutrophil protein may be detected in the stool. Thus, fecal calprotectin levels may assist in diagnosis of inflammatory bowel disease; Crohn's disease and ulcerative colitis and other disorders characterized by bowel inflammation. It can also be used as an aid in the differentiation of IBD from irritable bowel syndrome.

Test Resources

Algorithm

Differential Diagnosis of Inflammatory Bowel Disease

Clinical Focus

Inflammatory Bowel Disease: Laboratory Support for Diagnosis and Management

Test Details

Methodology

Chemiluminescence (CL)

Reference Range(s)

<50 mcg/g	Normal
50-120 mcg/g	Borderline
>120 mcg/g	Elevated

Alternative Name(s)

Crohn's Disease,Ulcerative Colitis,Inflammatory Bowel Disease,Irritable Bowel Syndrome

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Chemiluminescence (CL)

Reference Range(s)

<50 mcg/g	Normal
50-120 mcg/g	Borderline
>120 mcg/g	Elevated

Alternative Name(s)

Crohn's Disease,Ulcerative Colitis,Inflammatory Bowel Disease,Irritable Bowel Syndrome

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

3 grams solid stool collected in a Quest standard stool container without preservative or a clean, leak-proof plastic screw-cap container without preservative

Alternative Specimen(s)

Liquid or semi-liquid stool collected in a Quest standard stool container without preservative or a clean, leak-proof, plastic screw-cap container without preservative

Minimum Volume

0.3 g

Collection Instructions

Collect stool specimen in a clean leak-proof plastic screw-cap container without preservative. Quest standard stool container without preservative is available through Client Supply.

Room temperature stability: Stable for 6 days. However due to the sample type, it is not recommended to keep stool sample at Room Temperature.

Transport Container

Sterile leak-proof container

Transport Temperature

Frozen

Specimen Stability

Room temperature: 6 days
Refrigerated: 7 days
Frozen -20° C: 28 days
Frozen -70° C: 1 year

Reject Criteria

Stool specimen collected in a container with fixative or preservative • Stool specimen collected during surgical procedure • Other specimen rather than raw stool sample

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

3 grams solid stool collected in a Quest standard stool container without preservative or a clean, leak-proof plastic screw-cap container without preservative

Alternative Specimen(s)

Liquid or semi-liquid stool collected in a Quest standard stool container without preservative or a clean, leak-proof, plastic screw-cap container without preservative

Minimum Volume

0.3 g

Collection Instructions

Transport Container

Sterile leak-proof container

Transport Temperature

Frozen

Specimen Stability

Room temperature: 6 days
Refrigerated: 7 days
Frozen -20° C: 28 days
Frozen -70° C: 1 year

Reject Criteria

Stool specimen collected in a container with fixative or preservative • Stool specimen collected during surgical procedure • Other specimen rather than raw stool sample

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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