PTH, Intact, Fine Needle Aspirate

PTH, Intact, Fine Needle Aspirate

Test Code

16560
83970
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
16560
83970
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

PTH, Intact, Fine Needle Aspirate - Surgical treatment of hyperparathyroidism relies on the ability to accurately identify parathyroid tissue. The use of fine-needle aspirate (FNA) with measurement of intact parathyroid hormone (PTH) levels in suspected parathyroid cysts or adenomas is used to identify parathyroid tissue and has been proven to be a useful surgical adjunct in the treatment of hyperparathyroidism.

Test Resources

None found for this test
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Test Details

Methodology

Beckman Coulter Chemiluminescent

Reference Range(s)

Not suggestive of parathyroid tissue<30 pg/mL
Compatible with parathyroid tissue>100 pg/mL
Levels >1000 pg/mL suggestive of pathologic parathyroid lesion

Alternative Name(s)

PTHI,Intact Parathyroid Hormone FNA

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Beckman Coulter Chemiluminescent

Reference Range(s)

Not suggestive of parathyroid tissue<30 pg/mL
Compatible with parathyroid tissue>100 pg/mL
Levels >1000 pg/mL suggestive of pathologic parathyroid lesion

Alternative Name(s)

PTHI,Intact Parathyroid Hormone FNA
Service Area must be determined

Preferred Specimen(s)

1 mL fine needle aspirate (FNA) collected in a sterile transport tube

Alternative Specimen(s)

Parathyroid-tissue washings • Non-lymph node washings • Non-nodal soft tissue washings or cervical node washings collected in a sterile transport tube

Minimum Volume

0.8 mL

Collection Instructions

A 25-gauge needle is inserted obliquely within the transducer plane of view and moved back and forth (passes) through the nodule to compensate for patient movement and needle deflection. There is no suction device; cells move into the needle via capillary action. After collection of the cytology samples, withdraw between 0.10 and 0.25 mL of saline up through each needle and empty this fluid back through the needle into a tube. This is the needle washing used for analysis. Repeat the passes and saline washings from the same biopsied site and empty contents into the same tube. The washes from all needles are pooled (final volume 1 mL). Inspect specimen for visible blood or tissue contamination. If bloody, centrifuge specimen and transfer supernatant to a new tube to send to the laboratory. The supernatant, not the cellular materials, is used for analysis. If the specimen is clear, centrifugation is not necessary.
Freeze immediately and transport frozen sample to laboratory directly. Do not send specimens in glass tubes.

Transport Container

Sterile transport tube

Transport Temperature

Frozen

Specimen Stability

  • Room temperature: 2 hours
  • Refrigerated: 48 hours
  • Frozen: 28 days

Reject Criteria

Gross hemolysis • Specimens in glass tubes • Any specimen type other than those listed in the Preferred Specimen(s) or Alternative Specimen(s) sections

Setup Schedule

Service Area must be determined
1 mL fine needle aspirate (FNA) collected in a sterile transport tube
Parathyroid-tissue washings • Non-lymph node washings • Non-nodal soft tissue washings or cervical node washings collected in a sterile transport tube
0.8 mL
A 25-gauge needle is inserted obliquely within the transducer plane of view and moved back and forth (passes) through the nodule to compensate for patient movement and needle deflection. There is no suction device; cells move into the needle via capillary action. After collection of the cytology samples, withdraw between 0.10 and 0.25 mL of saline up through each needle and empty this fluid back through the needle into a tube. This is the needle washing used for analysis. Repeat the passes and saline washings from the same biopsied site and empty contents into the same tube. The washes from all needles are pooled (final volume 1 mL). Inspect specimen for visible blood or tissue contamination. If bloody, centrifuge specimen and transfer supernatant to a new tube to send to the laboratory. The supernatant, not the cellular materials, is used for analysis. If the specimen is clear, centrifugation is not necessary.
Freeze immediately and transport frozen sample to laboratory directly. Do not send specimens in glass tubes.
Sterile transport tube
Frozen
Room temperature: 2 hours
Refrigerated: 48 hours
Frozen: 28 days
Gross hemolysis • Specimens in glass tubes • Any specimen type other than those listed in the Preferred Specimen(s) or Alternative Specimen(s) sections
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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