Calcium, 24-Hour Urine with Creatinine
Test Code
Clinical Significance
Calcium, 24-Hour Urine with Creatinine -
This quantitative test, performed with a 24-hour urine specimen, may help screen for hypercalciuria, one of the established risk factors for kidney stone formation [1-3]. This test may also help assess metabolic disorders of calcium metabolism, such as hyperparathyroidism, bone disease, and idiopathic hypercalciuria. In general, 24-hour urine specimens are preferred to random urine specimens when measuring calcium for diagnostic evaluation of hypercalciuria [1].
Calcium is essential for bone formation and nerve, muscle, and heart functions. Calcium metabolism is jointly regulated by parathyroid ...
Test Resources
Clinical Focus
Autoimmune Rheumatic and Related DiseasesTest Details
Methodology
Reference Range(s)
| Male | 55-300 mg/24 h | |
| Female | 35-250 mg/24 h | |
| Male | 55-200 mg/24 h |
| Female | 35-200 mg/24 h |
Calcium/Creatinine Ratio
| Male | 30-210 mg/g creat | |
| Female | 30-275 mg/g creat | |
Creatinine, 24-Hour Urine
| <3 Years | Not established |
| 3-8 Years | 0.10-0.80 g/24 h |
| 9-12 Years | 0.20-1.40 g/24 h |
| 13-17 Years | 0.40-1.90 g/24 h |
| >17 Years | 0.50-2.15 g/24 h |
Preferred Specimen(s)
10 mL aliquot of a well-mixed, 24-hour collection
Collection Instructions
Refrigerate during and after collection. Collect urine with 25 mL of 6N HCl to maintain a pH <2. Do not include first morning specimen; collect all subsequent voidings. The last specimen collected should be the first morning specimen voided the following morning at the same time as the previous morning's first voiding.
Specify 24-hour total volume and collection duration on specimen container and test requisition.
Transport Container
Plastic screw-cap container
Transport Temperature
Room temperature
Setup Schedule, Alternative Specimen(s), Minimum Volume, Specimen Stability
Specify 24-hour total volume and collection duration on specimen container and test requisition.