Thrombopoietin (TPO)

Thrombopoietin (TPO)

Test Code

16336
83520
16336
83520
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Thrombopoietin (TPO) - This test will be used to measure serum TPO level in patients with thrombocytopenia of unknown cause. ITP (Idiopathic Thrombocytopenia purpura) is a common cause of thrombocytopenia. The diagnosis is based on exclusion criteria. Serum TPO levels are normal or only slightly elevated in ITP so that if TPO level is markedly elevated the diagnosis of ITP is strongly in doubt. Markedly elevated TPO levels may occur in individuals with genetic mutations of CD110. New Drugs, non peptide thrombopoietin receptor agonist (CD110) are becoming increasingly used in patients with thrombocytopenia of ITP. The ...

Test Resources

None found for this test
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Test Details

Methodology

Immunoassay (IA)

Assay Category

This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.

Reference Range(s)

7-99 pg/mL

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Immunoassay (IA)
This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.

Reference Range(s)

7-99 pg/mL
Service Area must be determined

Preferred Specimen(s)

1 mL frozen serum collected in SST (red-top/plastic) tube

Minimum Volume

0.5 mL

Collection Instructions

Cytokine levels may demonstrate diurnal variation. Recommend cytokine levels be determined at the same time of day for improved longitudinal comparison.

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

  • Room Temperature: Unacceptable
  • Refrigerated: Unacceptable
  • Frozen -20° C: 30 days
  • Frozen -70° C: 7 months

Reject Criteria

Grossly lipemic • Grossly icteric • Received room temperature • Received refrigerated

Setup Schedule

Service Area must be determined
1 mL frozen serum collected in SST (red-top/plastic) tube
0.5 mL
Cytokine levels may demonstrate diurnal variation. Recommend cytokine levels be determined at the same time of day for improved longitudinal comparison.
Transport tube
Frozen
Room Temperature: Unacceptable
Refrigerated: Unacceptable
Frozen -20° C: 30 days
Frozen -70° C: 7 months
Grossly lipemic • Grossly icteric • Received room temperature • Received refrigerated
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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