Osteocalcin, N-MID

Test Code

16322

CPT Code(s)

83937

Test Code

16322

CPT Code(s)

83937

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Osteocalcin, N-MID - Osteocalcin, the most abundant non-collagen protein in bone matrix, is a bone-specific, calcium binding protein. Serum osteocalcin levels are related to the rate of bone turnover in various disorders of bone metabolism, e.g., osteoporosis, primary and secondary hyperparathyroidism, and Paget's disease.

Test Resources

Test FAQ

Biotin: Interference with Laboratory Assays

Test Details

Patient Preparation

Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.

Methodology

Electrochemiluminescence Immunoassay (ECLIA)

Reference Range(s)

	Male (ng/mL)	Female (ng/mL)
0-4 Years	Not established	Not established
5-9 Years	47-142	47-142
10-13 Years	49-167	49-167
14-17 Years	26-203	14-85
>17 Years	9-38	8-32

LOINC® Codes, Performing Laboratory

Service Area must be determined

Patient Preparation

Methodology

Electrochemiluminescence Immunoassay (ECLIA)

Reference Range(s)

	Male (ng/mL)	Female (ng/mL)
0-4 Years	Not established	Not established
5-9 Years	47-142	47-142
10-13 Years	49-167	49-167
14-17 Years	26-203	14-85
>17 Years	9-38	8-32

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Collection Instructions

Allow blood to clot at room temperature (20-26° C) and centrifuge immediately to separate the serum from the cells. Freeze as soon as possible.

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 24 hours
Frozen 21 days

Reject Criteria

Hemolysis • Heat inactivated specimens • Specimens stabilized with azide • Patient administered with biotin within 8 hours

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Collection Instructions

Allow blood to clot at room temperature (20-26° C) and centrifuge immediately to separate the serum from the cells. Freeze as soon as possible.

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 24 hours
Frozen 21 days

Reject Criteria

Hemolysis • Heat inactivated specimens • Specimens stabilized with azide • Patient administered with biotin within 8 hours

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.