Tick-Borne Disease Antibodies Panel with Reflexes
Test Code
16220
86618, 86666 (x4), 86753 (x2)
Clinical Significance
Tick-Borne Disease Antibodies Panel with Reflexes - This panel contains components for the detection of antibodies against Borrelia burgdorferi (Lyme disease) using the modified two-tier algorithm, Anaplasma phagocytophilum, Ehrlichia chaffeensis, and Babesia microti. Infection with these organisms can occur from the bite of a tick found in endemic regions, including the upper Northeast and Midwestern United States. Appropriate reflex testing of individual components is performed for initial screen results.
The tests included in the panel are serologic assays used to aid in the diagnosis of select tickborne related ...
Test Resources
Clinical Focus
Lyme Disease: Laboratory Support of Diagnosis and ManagementTest Details
Lyme Disease Antibody with Reflex to Immunoassay (IgG, IgM) (MTTT)
Anaplasma phagocytophilum Antibodies (IgG, IgM) with Reflex to Titer
Babesia microti Antibodies (IgG, IgM) with Reflex to Titers
Ehrlichia chaffeensis Antibodies (IgG, IgM) with Reflex to Titers
If Lyme Disease Antibody is Positive or Equivocal (≥0.90), then Lyme Disease Supplemental Antibodies (IgG, IgM), Immunoassay will be performed at an additional charge (CPT code(s): 86617(x2)).
If A. phagocytophilum (IgG) is Detected, then A. phagocytophilum (IgG) Titer will be performed at an additional charge (CPT code(s): 86317).
If A. phagocytophilum (IgM) is Detected, then A. phagocytophilum (IgM) Titer will be performed at an additional charge (CPT code(s): 86317).
If Babesia microti (IgG) is Detected, then Babesia microti (IgG) Titer will be performed at an additional charge (CPT code(s): 86317).
If Babesia microti (IgM) is Detected, then Babesia microti (IgM) Titer will be performed at an additional charge (CPT code(s): 86317).
If E. chaffeensis (IgG) is Detected, then E. chaffeensis (IgG) Titer will be performed at an additional charge (CPT code(s): 86317).
If E. chaffeensis (IgM) is Detected, then E. chaffeensis (IgM) Titer will be performed at an additional charge (CPT code(s): 86317).
Anaplasma phagocytophilum Antibodies (IgG, IgM) with Reflex to Titer
Babesia microti Antibodies (IgG, IgM) with Reflex to Titers
Ehrlichia chaffeensis Antibodies (IgG, IgM) with Reflex to Titers
If Lyme Disease Antibody is Positive or Equivocal (≥0.90), then Lyme Disease Supplemental Antibodies (IgG, IgM), Immunoassay will be performed at an additional charge (CPT code(s): 86617(x2)).
If A. phagocytophilum (IgG) is Detected, then A. phagocytophilum (IgG) Titer will be performed at an additional charge (CPT code(s): 86317).
If A. phagocytophilum (IgM) is Detected, then A. phagocytophilum (IgM) Titer will be performed at an additional charge (CPT code(s): 86317).
If Babesia microti (IgG) is Detected, then Babesia microti (IgG) Titer will be performed at an additional charge (CPT code(s): 86317).
If Babesia microti (IgM) is Detected, then Babesia microti (IgM) Titer will be performed at an additional charge (CPT code(s): 86317).
If E. chaffeensis (IgG) is Detected, then E. chaffeensis (IgG) Titer will be performed at an additional charge (CPT code(s): 86317).
If E. chaffeensis (IgM) is Detected, then E. chaffeensis (IgM) Titer will be performed at an additional charge (CPT code(s): 86317).
Methodology
See individual tests
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
| Lyme Ab, Screen | <0.90 index |
| A. phagocytophilum Ab (IgG), Screen | Not Detected |
| A. phagocytophilum Ab (IgM), Screen | Not Detected |
| Babesia microti Ab (IgG), Screen | Not Detected |
| Babesia microti Ab (IgM), Screen | Not Detected |
| E. chaffeensis Ab (IgG), Screen | Not Detected |
| E. chaffeensis Ab (IgM), Screen | Not Detected |
| Lyme Ab (IgG) | <0.90 index |
| Lyme Ab (IgM) | <0.90 index |
| A. phagocytophilum Ab (IgG), Titer | <1:64 titer |
| A. phagocytophilum Ab (IgM), Titer | <1:20 titer |
| Babesia microti Ab (IgG), Titer | <1:64 titer |
| Babesia microti Ab (IgM), Titer | <1:20 titer |
| E. chaffeensis Ab (IgG), Titer | <1:64 titer |
| E. chaffeensis Ab (IgM), Titer | <1:20 titer |
Alternative Name(s)
Anaplasma Phagocytophilum Ab,Babesia Microti Antibodies,Ehrlichia Chaffeensis Ab,Lyme Disease Ab w/Refl
Preferred Specimen(s)
2 mL serum
Minimum Volume
1.5 mL
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
- Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 30 days
Setup Schedule
2 mL serum
1.5 mL
Transport tube
Refrigerated (cold packs)
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days