Pancreatic Exocrine Cell Antibody
Test Code
16143
86255
Clinical Significance
Pancreatic Exocrine Cell Antibody - Antibodies to pancreatic exocrine cells (ExPA) have been suggested as a very specific Crohn's Disease (CD) serological marker. Clinical studies reported a prevalence of 30-50% in CD patients. In spite of the relatively low sensitivity, ExPA can detect a subpopulation of CD patients that are negative for other CD markers (ASCA IgG, ASCA IgA), thus being very useful in combination with other IBD tests.
Test Resources
None found for this test
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Test Details
Methodology
Immunofluorescence Assay (IFA)
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
Negative