First Trimester Screen, Hyperglycosylated hCG (h-hCG)
Test Code
16020
81508
Clinical Significance
First Trimester Screen, Hyperglycosylated hCG (h-hCG) - To screen for Down syndrome and trisomy 18 at 9.0-13.9 weeks gestation.
Test Resources
Test Details
PAPP-A (Pregnancy-associated Plasma Protein), h-hCG (hyperglycosylated hCG), risk calculation which includes NT (Nuchal Translucency)
Methodology
Chemiluminescence (CL) • Immunoassay (IA)
h-hCG: This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
PAPP-A: This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.
This test code is for non-New York patient testing. For New York patient testing, use test code 16969.
This test is not available for California patient testing.
PAPP-A: This test was performed using a kit that has not been cleared or approved by the FDA. The analytical performance characteristics of this test have been determined by Quest Diagnostics. This test should not be used for diagnosis without confirmation by other medically established means.
This test code is for non-New York patient testing. For New York patient testing, use test code 16969.
This test is not available for California patient testing.
Alternative Name(s)
Invasive Trophoblast Antigen (ITA),Nuchal Translucency (NT),Hyperglycosylated hCG (h-hCG),Pregnancy-associated Plasma Protein-A (PAPP-A),MSS, 1st Trimester,Down Syndrome and Trisomy 18 Screen
Preferred Specimen(s)
1.5 mL serum
Minimum Volume
0.8 mL
Transport Container
Transport tube
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 14 days
- Refrigerated: 14 days
- Frozen: 28 days
Reject Criteria
Moderate and gross hemolysis • Lipemia
Setup Schedule
1.5 mL serum
0.8 mL
Transport tube
Room temperature
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 28 days
Refrigerated: 14 days
Frozen: 28 days
Moderate and gross hemolysis • Lipemia