dRVVT Screen with Reflex to dRVVT Confirm and dRVVT 1:1 Mix

dRVVT Screen with Reflex to dRVVT Confirm and dRVVT 1:1 Mix

Test Code

15780
85613
15780
85613
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

dRVVT Screen with Reflex to dRVVT Confirm and dRVVT 1:1 Mix - The dilute Russell Viper Venom time integrated test is a sensitive method for the detection of Lupus Anticoagulants (LA). LA are autoantibodies that target protein-phospholipid complexes and are found in a variety of clinical conditions. In some patients, a confirmed positive result is associated with an increased thrombotic risk, and is often found in women who have recurrent fetal loss. As Lupus anticoagulants reflect a heterogenous group of antibodies, international consensus guidelines on testing require at least two screening assays be used for a complete evaluation. Refer to Lupus Anticoagulant ...

Test Resources

None found for this test
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Test Details

Includes

  • If dRVVT Screen is prolonged (>45 seconds), then dRVVT Confirm will be performed at an additional charge (CPT code(s): 85597).
  • If dRVVT Confirm is positive, then dRVVT 1:1 Mixing Study will be performed at an additional charge (CPT code(s): 85613).

Methodology

Clot Detection

Reference Range(s)

dRVVT Screen≤45 seconds
  dRVVT ConfirmNegative
  dRVVT 1:1 MixCorrected

Alternative Name(s)

Dilute Russell Viper Venom

LOINC® Codes, Performing Laboratory

If dRVVT Screen is prolonged (>45 seconds), then dRVVT Confirm will be performed at an additional charge (CPT code(s): 85597).
If dRVVT Confirm is positive, then dRVVT 1:1 Mixing Study will be performed at an additional charge (CPT code(s): 85613).

Methodology

Clot Detection

Reference Range(s)

dRVVT Screen≤45 seconds
  dRVVT ConfirmNegative
  dRVVT 1:1 MixCorrected

Alternative Name(s)

Dilute Russell Viper Venom

Preferred Specimen(s)

1 mL frozen platelet-poor plasma collected in a 3.2% sodium citrate (light blue-top) tube

Minimum Volume

0.5 mL

Collection Instructions

Please submit a separate, frozen vial for each special coagulation assay ordered. Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice.

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

  • Room temperature: Unacceptable
  • Refrigerated: Unacceptable
  • Frozen: 90 days

Reject Criteria

Hemolysis

Setup Schedule

1 mL frozen platelet-poor plasma collected in a 3.2% sodium citrate (light blue-top) tube
0.5 mL
Please submit a separate, frozen vial for each special coagulation assay ordered. Draw blood in a light blue-top tube containing 3.2% sodium citrate, mix gently by inverting 3-4 times. Centrifuge 15 minutes at 1500 g within one hour of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial(s). Freeze immediately and transport on dry ice.
Transport tube
Frozen
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 90 days
Hemolysis
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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