HLA-B27 DNA Typing

HLA-B27 DNA Typing

Test Code

15584
81374
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
15584
81374
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

HLA-B27 DNA Typing - This test is used in the evaluation of genetic risk for Ankylosing Spondylitis, uveitis, and several other autoimmune disorders.

Test Resources

Test Summary

HLA-B27

Test Details

Methodology

Polymerase Chain Reaction (PCR) • Sequence Specific Oligonucleotide Probes

Reference Range(s)

Negative

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Polymerase Chain Reaction (PCR) • Sequence Specific Oligonucleotide Probes

Reference Range(s)

Negative
Service Area must be determined

Preferred Specimen(s)

5 mL whole blood collected in an EDTA (lavender-top) tube

Alternative Specimen(s)

Whole blood collected in: Sodium heparin (green-top) tube, EDTA (pink-top) tube, EDTA (royal blue-top) tube, or 3.2% sodium citrate (light blue-top) tube

Minimum Volume

3 mL

Collection Instructions

A separate EDTA (lavender-top) tube must be submitted for all HLA testing. If submitted with any other test requiring an EDTA tube, please submit a separate tube for this test. Do not open tube.

Transport Container

EDTA (lavender-top) tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 7 days
  • Frozen: Unacceptable

Reject Criteria

Received frozen • Clotted

Setup Schedule

Service Area must be determined
5 mL whole blood collected in an EDTA (lavender-top) tube
Whole blood collected in: Sodium heparin (green-top) tube, EDTA (pink-top) tube, EDTA (royal blue-top) tube, or 3.2% sodium citrate (light blue-top) tube
3 mL
A separate EDTA (lavender-top) tube must be submitted for all HLA testing. If submitted with any other test requiring an EDTA tube, please submit a separate tube for this test. Do not open tube.
EDTA (lavender-top) tube
Room temperature
Room temperature: 7 days
Refrigerated: 7 days
Frozen: Unacceptable
Received frozen • Clotted
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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