Albumin, 24-Hour Urine with Creatinine
Test Code
15281
82043, 82570
Clinical Significance
Albumin, 24-Hour Urine with Creatinine - Albumin excreted in the urine (Microalbumin) is a sensitive marker of Nephropathy. It is used to screen for early renal disease in diabetic patients.
Test Details
CPT code 81050 may be added at an additional charge for volume measurement
Methodology
Turbidometric
Reference Range(s)
| Albumin, 24 hour urine | <30 mg/24 h |
| Albumin, 24 hour urine | <20 mcg/min |
Creatinine, 24-Hour Urine
| <3 Years | Not established |
| 3-8 Years | 0.10-0.80 g/24 h |
| 9-12 Years | 0.20-1.40 g/24 h |
| 13-17 Years | 0.40-1.90 g/24 h |
| >17 Years | 0.50-2.15 g/24 h |
The ADA defines abnormalities in albumin excretion as follows:
| Category | Result (mg/24 h) | Result (mcg/min) |
| Normal | <30 | <20 |
| Microalbuminuria | 30-299 | 20-199 |
| Clinical Albuminuria | ≥300 | ≥200 |
Preferred Specimen(s)
5 mL urine aliquot from a well-mixed 24-hour urine collection - no preservative
Alternative Specimen(s)
Urinalysis transport tube (yellow-top, blue fill line, preservative tube)
Minimum Volume
2 mL
Collection Instructions
Specify 24-hour total volume on container and test requisition.
Note: Exercise within 24 hours, infection, fever, congestive heart failure, marked hyperglycemia, and marked hypertension may elevate urinary albumin excretion over baseline values.
Transport Container
Plastic urine container
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 7 days
- Refrigerated: 7 days
- Frozen: 28 days
Reject Criteria
Acid preserved urine
Setup Schedule
5 mL urine aliquot from a well-mixed 24-hour urine collection - no preservative
Urinalysis transport tube (yellow-top, blue fill line, preservative tube)
2 mL
Specify 24-hour total volume on container and test requisition.
Note: Exercise within 24 hours, infection, fever, congestive heart failure, marked hyperglycemia, and marked hypertension may elevate urinary albumin excretion over baseline values.
Note: Exercise within 24 hours, infection, fever, congestive heart failure, marked hyperglycemia, and marked hypertension may elevate urinary albumin excretion over baseline values.
Plastic urine container
Room temperature
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 28 days
Acid preserved urine