Cyclosporine A Trough, LC/MS/MS, Blood
Test code
CPT code(s)*
Details
Methodology
Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Assay category
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Specimen requirements | |
|---|---|
| Patient preparation | Optimum time to collect sample is 1 hour before next dose |
| Preferred specimen(s) | 5 mL whole blood collected in an EDTA (lavender-top) tube |
| Alternative specimen(s) | Whole blood collected in: Sodium heparin (green-top) tube |
| Minimum volume | 2 mL |
| Transport container | EDTA (lavender-top) tube |
| Transport temperature | Room temperature |
| Specimen stability | Room temperature: 7 days Refrigerated: 6 days Frozen: Unacceptable |
| Reject criteria | Clotted specimen |
Reference Range(s)
No definitive therapeutic or toxic ranges have been established. Opitmal blood drug levels are influenced by type of transplant, patient response, time post-transplant, co-administration of other drugs, and drug formulation.
The following trough ranges are suggested guidelines:
| Kidney Transplantation | 100-200 mcg/L |
| Other Organ Transplant | 200-300 mcg/L |
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
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