Kappa Light Chain, Free, Urine
Test Code
Clinical Significance
Kappa Light Chain, Free, Urine - Kappa/Lambda Light Chains, Free with Ratio, Urine by turbidimetry provides a sensitive detection and quantitation of free light chains (FLCs) in urine earlier than electrophoresis and immunofixation. Urinary FLCs (uFLCs) are known as Bence-Jones Proteins (BJP).
Abnormal levels of FLCs are commonly produced in a constellation of disorders referred as Plasma Cell Dyscrasia producing monoclonal gammopathies (MG), which constitutes neoplastic growth of plasma cell lines that secrete monoclonal proteins, either as intact immunoglobulins, or isolated light chains as in Light Chain Multiple Myeloma ...
Test Resources
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Test Details
Preferred Specimen(s)
2 mL urine collected in a plastic leak-proof container
Alternative Specimen(s)
24-hour urine, unpreserved
Minimum Volume
1 mL
Transport Container
Plastic leak-proof container
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 7 days
- Refrigerated: 21 days
- Frozen: 30 days
Reject Criteria
Gross hemolysis • Microbial contamination
Setup Schedule
Refrigerated: 21 days
Frozen: 30 days