Endomysial Antibody (IgA) Screen with Reflex to Titer

Test Code

15064

CPT Code(s)

86231

Test Code

15064

CPT Code(s)

86231

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Endomysial Antibody (IgA) Screen with Reflex to Titer - The presence of anti-endomysial (EMA) IgA antibodies has been shown to correlate with gluten-sensitive enteropathy such as celiac disease (CD) and dermatitis herpetiformis (DH). EMA is detected primarily by IFA, using monkey esophagus as a substrate and observing fluorescence of the endomysial lining. Patients with CD and DH can also demonstrate antibodies to reticulin and gliadin, though EMA-IgA seems to be the most specific marker (specifically 94-100%).

Test Resources

Test Summary

Celiac Disease Comprehensive Panel With Gliadin Antibody (IgG)

Test Details

Includes

If Endomysial Antibody (IgA) Screen is positive, then Endomysial Antibody Titer will be performed at an additional charge (CPT code(s): 86231).

Methodology

Immunofluorescence Assay (IFA)

Reference Range(s)

Endomysial Antibody (IgA)	Negative
Endomysial Antibody Titer	<1:5

LOINC® Codes, Performing Laboratory

Service Area must be determined

Includes

If Endomysial Antibody (IgA) Screen is positive, then Endomysial Antibody Titer will be performed at an additional charge (CPT code(s): 86231).

Methodology

Immunofluorescence Assay (IFA)

Reference Range(s)

Endomysial Antibody (IgA)	Negative
Endomysial Antibody Titer	<1:5

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.3 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 21 days
Frozen: 21 days

Reject Criteria

Gross hemolysis • Grossly lipemic

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.3 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Refrigerated: 21 days
Frozen: 21 days

Reject Criteria

Gross hemolysis • Grossly lipemic

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection may be available in your area for purchase through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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