Beta-Globin Complete

Test code

14974

CPT code(s)*

81364

In-home collection is not available in your area through Quest Mobile.

Clinical significance

Beta-Globin Complete - 1) To identify disease-causing mutations in individuals affected with beta-thalassemia.
2) To identify carriers in high-risk ethnic group or people with positive family history.
3) Prenatal diagnosis of beta-thalassemia.

Test resources

Test FAQ

Beta-Globin Complete

Details

Test details

Methodology

DNA Sequencing • Polymerase Chain Reaction (PCR)

Assay category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Alternative name(s)

Beta-Thalassemia Mutation Analysis

Specimen requirements
Patient preparation	None Specified
Preferred specimen(s)	5 mL whole blood collected in a EDTA (lavender-top), or ACD (yellow-top) tube
Alternative specimen(s)	Sodium heparin (green-top) tube
Minimum volume	3 mL
Collection instructions	Whole blood: Normal phlebotomy procedure. Specimen stability is crucial. Store and ship ambient immediately. Glass tubes should not be shipped frozen.
Transport temperature	Room temperature
Specimen stability	Room temperature: 30 days Refrigerated: 30 days Frozen: 30 days

Reference range(s)

See Laboratory Report

LOINC® codes

The Result and LOINC® information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table are not orderable Test Codes

Result code	Result name	LOINC code	Component name
85998155	Beta-Globin DNA Mutations	50996-8	HBB gene targeted mutation analysis
86007537	CLINCAL INDICATION:	55752-0	Clinical information
86007538	Referring Physician:	46608-6	Primary referring physician ID
86007542	Physicians Phone number:	81230-5	Referring physician phone number
86007572	Ethnicity	32624-9	Race

Performing lab & setup schedule

Performing laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Setup schedule

Set up: Mon, Thurs; Report available: 15 days

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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