Lipid Panel with Reflex to Direct LDL

Lipid Panel with Reflex to Direct LDL

Test Code

14852
80061
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
14852
80061
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Lipid Panel with Reflex to Direct LDL - The Lipid Panel with Reflex to Direct LDL panel includes evaluation of total cholesterol, HDL-cholesterol, triglyceride (TG), LDL-cholesterol (calculated), cholesterol/HDL ratio (calculated), and non-HDL cholesterol; direct LDL-C measurement will be performed at additional cost if the TG level is >400 mg/dL. This panel is useful in the detection, classification, and monitoring of hyperlipidemia, especially those expected to have highly elevated TG levels.

LDL-C is widely accepted as a key factor for assessing the risk of coronary artery disease (CAD) [1]. The American Heart Association ...

Test Resources

Test FAQ

LDL Cholesterol Calculations

Clinical Focus

Polycystic Ovary Syndrome (PCOS)

Test Summary

LDL Cholesterol

Test Details

Includes

  • Cholesterol, Total
  • Triglycerides
  • HDL Cholesterol
  • LDL-Cholesterol (calculated)
  • Cholesterol/HDL Ratio (calculated)
  • Non-HDL Cholesterol (calculated)
  •  
  • If Triglyceride result is >400 mg/dL, then Direct LDL will be performed at an additional charge (CPT code(s): 83721).

Patient Preparation

Fasting is not required prior to collection of a lipid panel. The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been. . . determined to interfere with assays for. . . cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hrs and a third dose of 100 mg/kg administered over 16 hrs.

Methodology

Spectrophotometry (SP)

Reference Range(s)


Total Cholesterol 		Male
(mg/dL) 		Female
(mg/dL)
<20 Years <170 <170
≥20 Years <200 <200
HDL Cholesterol    
<20 Years >45 >45
≥20 Years ≥40 ≥50
Triglycerides    
≤9 Years <75 <75
10-19 Years <90 <90
≥20 Years <150 <150
LDL-Cholesterol (Calc)    
<20 Years <110 <110
≥20 Years <100 <100
Cholesterol/HDL Ratio (Calc) <5.0 <5.0
Non-HDL Cholesterol    
<20 Years <120 <120
≥20 Years <130 <130

Alternative Name(s)

Non-fasting Lipid Panel with Reflex

LOINC® Codes, Performing Laboratory

Service Area must be determined
Cholesterol, Total
Triglycerides
HDL Cholesterol
LDL-Cholesterol (calculated)
Cholesterol/HDL Ratio (calculated)
Non-HDL Cholesterol (calculated)

If Triglyceride result is >400 mg/dL, then Direct LDL will be performed at an additional charge (CPT code(s): 83721).
Fasting is not required prior to collection of a lipid panel. The assay manufacturer Beckman Coulter advises: "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been. . . determined to interfere with assays for. . . cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regimen consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hrs and a third dose of 100 mg/kg administered over 16 hrs.

Methodology

Spectrophotometry (SP)

Reference Range(s)


Total Cholesterol 		Male
(mg/dL) 		Female
(mg/dL)
<20 Years <170 <170
≥20 Years <200 <200
HDL Cholesterol    
<20 Years >45 >45
≥20 Years ≥40 ≥50
Triglycerides    
≤9 Years <75 <75
10-19 Years <90 <90
≥20 Years <150 <150
LDL-Cholesterol (Calc)    
<20 Years <110 <110
≥20 Years <100 <100
Cholesterol/HDL Ratio (Calc) <5.0 <5.0
Non-HDL Cholesterol    
<20 Years <120 <120
≥20 Years <130 <130

Alternative Name(s)

Non-fasting Lipid Panel with Reflex
Service Area must be determined

Preferred Specimen(s)

2 mL serum

Alternative Specimen(s)

Plasma collected in: Sodium heparin (green-top) tube or lithium heparin (green-top) tube

Collection Instructions

Centrifuge within 30-60 minutes following collection

Transport Container

Serum separator tube (SST)

Transport Temperature

Room temperature

Specimen Stability

  • Serum
  • Room temperature: 48 hours
  • Refrigerated: 7 days
  • Frozen: 28 days
  •  
  • Plasma
  • Room temperature: 48 hours
  • Refrigerated: 48 hours
  • Frozen: 28 days

Reject Criteria

Gross hemolysis • Moderate to gross icterus • Anticoagulants other than heparin

Setup Schedule

Service Area must be determined
2 mL serum
Plasma collected in: Sodium heparin (green-top) tube or lithium heparin (green-top) tube
Centrifuge within 30-60 minutes following collection
Serum separator tube (SST)
Room temperature
Serum
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 28 days

Plasma
Room temperature: 48 hours
Refrigerated: 48 hours
Frozen: 28 days
Gross hemolysis • Moderate to gross icterus • Anticoagulants other than heparin
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.

Customize the test information for your Service Area