Dopamine, Urine

Dopamine, Urine

Test Code

14763
82542
14763
82542
Not offered in Quest Nichols Institute - Chantilly, VA | Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Dopamine, Urine - Measurement of dopamine levels in urine or blood in addition to urinary vanillylmandelic acid (VMA) and homovanillic acid (HVA) levels may aid in the biochemical diagnosis and monitoring of neuroblastomas [1]. This test may also be useful in evaluating dopamine-secreting pheochromocytomas and paragangliomas (PPGLs) [2].

Neuroblastomas occur predominantly in children and are the most common malignancy under 1 year old. Neuroblastomas are catecholamine-metabolizing tumors with limited ability to store and secrete catecholamines. Thus, catecholamine metabolites (including VMA and HVA) are more ...

Test Resources

None found for this test
Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.

Test Details

Includes

  • CPT code 81050 may be added at an additional charge for volume measurement

Patient Preparation

It is preferable for the patient to be off medications for three days prior to collection. However, common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference.
Patient should avoid alcohol, coffee, tea, tobacco and strenuous exercise prior to collection.

Methodology

Liquid Chromatography/Mass Spectrometry (LC/MS)

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

PediatricNot Established
Adult52-480 mcg/24 h

LOINC® Codes, Performing Laboratory

Service Area must be determined
CPT code 81050 may be added at an additional charge for volume measurement
It is preferable for the patient to be off medications for three days prior to collection. However, common antihypertensives (diuretics, ACE inhibitors, calcium channel blockers, alpha and beta blockers) cause minimal or no interference.
Patient should avoid alcohol, coffee, tea, tobacco and strenuous exercise prior to collection.

Methodology

Liquid Chromatography/Mass Spectrometry (LC/MS)
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

PediatricNot Established
Adult52-480 mcg/24 h
Service Area must be determined

Preferred Specimen(s)

1 mL preserved 24-hour urine with 25 mL 6N HCl collected in a 24-hour urine container

Alternative Specimen(s)

Unpreserved 24-hour urine collected in a sterile screw-cap container

Minimum Volume

0.7 mL

Transport Container

Plastic urine container

Transport Temperature

Frozen

Specimen Stability

  • Preserved urine
    Room temperature: Unacceptable
    Refrigerated: 30 days
    Frozen: 60 days

    Unpreserved urine
    Room temperature: Unacceptable
    Refrigerated: 7 days
    Frozen: 60 days

Setup Schedule, Collection Instructions, Reject Criteria

Service Area must be determined
1 mL preserved 24-hour urine with 25 mL 6N HCl collected in a 24-hour urine container
Unpreserved 24-hour urine collected in a sterile screw-cap container
0.7 mL

Plastic urine container

Frozen
Preserved urine
Room temperature: Unacceptable
Refrigerated: 30 days
Frozen: 60 days

Unpreserved urine
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 60 days
Service Area must be determined
Not offered in Quest Nichols Institute - Chantilly, VA | Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.

Customize the test information for your Service Area