Chromosome Analysis, POC Tissue

Test code

14593

CPT code(s)*

88233, 88262

**CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.

In-home collection is not available in your area through Quest Mobile.

Clinical significance

Chromosome Analysis, POC Tissue - Chromosome analysis of products of conception (POC) can detect fetal chromosome abnormalities, which are associated with approximately one-half of all first trimester spontaneous abortions. Chromosome testing on fibroblasts obtained from a tissue biopsy is performed to investigate tissue specific mosaicism not present in blood lymphocytes. Fresh cells from tissue biopsies obtained postmortem may still be suitable for chromosome analysis when the patient's blood is not available or viable. If chromosome analysis is unsuccessful, please contact the laboratory genetic counselor at 1-866-GENEINFO (1-866-436-3463) to discuss…

Test resources

Test FAQ

Chromosome Analysis, POC Tissue

Details

Test details

Methodology

Karyotype • Microscopy • Tissue Culture

Alternative name(s)

Karyotype

Specimen requirements
Patient preparation	None Specified
Preferred specimen(s)	5x5 mm tissue collected in a sterile container in Hanks', Ringer's solution, or culture medium with antibiotics
Alternative specimen(s)	Tissue in saline solution • Cultured cells collected in flasks
Minimum volume	2x3 mm
Collection instructions	Fetal tissue sample minimum of 2x3 mm collected in a sterile container with Hank's, Ringer's solution, culture medium with antibiotics, or saline solution. Transport media should be refrigerated before use, but can be shipped at room temperature.
Transport container	Sterile screw-cap container
Transport temperature	Room temperature
Specimen stability	Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.

Reference range(s)

See Laboratory Report

LOINC® codes

The Result and LOINC® information listed below should not be used for electronic interface maintenance with Quest Diagnostics. Please contact the Quest Diagnostics Connectivity Help Desk for more information at 800-697-9302.

NOTE: The codes listed in the table are not orderable Test Codes

Result code	Result name	LOINC code	Component name
86010959	CHROMOSOME ANALYSIS, POC TISSUE	29770-5	Karyotype

Performing lab & setup schedule

Performing laboratory

Quest Diagnostics Nichols Institute-Chantilly VA

14225 Newbrook Drive

Chantilly, VA 20151-2228

Setup schedule

Set up: Daily; Report available: 15 days

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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