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Chromosome Analysis, Chorionic Villus Sample

Test code

14592

CPT code(s)*

88235, 88267, 88280
Notices
**CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide Service Area Information to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical significance

Chromosome Analysis, Chorionic Villus Sample - This test will detect chromosome abnormalities of the fetus including numerical, structural, and mosaic abnormalities. Chromosome analysis will also reveal fetal gender and sex chromosome abnormalities. Indications for prenatal chromosome analysis may include advanced maternal age, abnormal fetal ultrasound, abnormal maternal serum screen, abnormal cell-free DNA results, history of a previous child with a chromosome abnormality, or a parent who carries a balanced chromosomal rearrangement or has another chromosome abnormality.
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Test resources

Test FAQ

Chromosome Analysis, Chorionic Villus Sample

Algorithm

Prenatal Screening and Diagnosis For Chromosomal Abnormalities Using Cell-Free DNA

Clinical focus

Prenatal Screening and Diagnosis of Fetal Chromosomal Abnormalities and Open Neural Tube Defects

Details

Test details

Methodology

Culture • Microscopy • Karyotype

Alternative name(s)

CVS, Chromosome Evaluation,CVS, Chromosome Study

Specimen requirements
Patient preparationNone Specified
Preferred specimen(s)40 mg chorionic villus sampling collected in CVS transport media
Minimum volume20 mg
Collection instructionsShip in sterile container in Hanks', Ringer's solution or culture medium with antibiotics. CVS media available upon request. Ship at room temperature.
Please contact the laboratory genetic counselor at 1-866-GENEINFO (1-866-436-3463) with any questions.
Transport containerGenetics transport pack
Transport temperatureRoom temperature
Specimen stabilitySpecimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject.
Service Area Information
Service Area Information

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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