Cardiometabolic Disease Assessment (CMDA) Panel

Includes

• Lipid Panel, Standard
  Apolipoprotein B
  Hemoglobin A1c
  Insulin Resistance Panel with Score
  TSH
  Albumin, Random Urine with Creatinine
  Comprehensive Metabolic Panel
  Fibrosis-4 (FIB-4) Index
  Platelet Count, EDTA
  Kidney Profile Comments
  
  Calculations typically used for Kidney Profile are intended to be reflected with the CMDA Panel. These calculations will utilize Creatinine with eGFR from the Comprehensive Metabolic Panel, in addition to the Albumin/Creatinine Ratio.

Patient Preparation

Patient should be fasting 9-12 hours

Additional Considerations for Patient Preparation:
Albumin, Random Urine with Creatinine: Exercise within 24 hours, infection, fever, congestive heart failure, marked hyperglycemia, and marked hypertension may elevate urinary albumin excretion over baseline values.

Cholesterol and Triglyceride testing: The assay manufacturer Beckman Coulter advises "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been determined to interfere with assays for cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regime consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours.

Comprehensive Metabolic Panel: Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods.

⁠⁠⁠⁠⁠⁠⁠TSH: Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks after angiography. According to the assay manufacturer Siemens: samples containing fluorescein can produce falsely depressed values.

Methodology

Spectrophotometry (SP) • Immunoturbidimetric • Enzymatic • Immunocapture Liquid Chromatography/Tandem Mass Spectrometry • Electronic Cell Sizing/Counting/Cytometry/Microscopy • Immunoassay (IA)

Reference Range(s)

See Laboratory Report

Alternative Name(s)

CMDA Panel

LOINC® Codes, Performing Laboratory