Cardiometabolic Disease Assessment (CMDA) Panel
Test code
CPT code(s)*
Clinical significance
Test resources
Test FAQ
Test summary
Details
Includes
Lipid Panel, Standard
Apolipoprotein B
Hemoglobin A1c
Insulin Resistance Panel with Score
TSH
Albumin, Random Urine with Creatinine
Comprehensive Metabolic Panel
Fibrosis-4 (FIB-4) Index
Platelet Count, EDTA
Kidney Profile Comments
Calculations typically used for Kidney Profile are intended to be reflected with the CMDA Panel. These calculations will utilize Creatinine with eGFR from the Comprehensive Metabolic Panel, in addition to the Albumin/Creatinine Ratio.
Methodology
Spectrophotometry (SP) • Immunoturbidimetric • Enzymatic • Immunocapture Liquid Chromatography/Tandem Mass Spectrometry • Electronic Cell Sizing/Counting/Cytometry/Microscopy • Immunoassay (IA)
Alternative name(s)
Cardiometabolic Panel,CMDA Panel
Specimen requirements | |
|---|---|
| Patient preparation | Patient should be fasting 9-12 hours Additional Considerations for Patient Preparation: Albumin, Random Urine with Creatinine: Exercise within 24 hours, infection, fever, congestive heart failure, marked hyperglycemia, and marked hypertension may elevate urinary albumin excretion over baseline values. Cholesterol and Triglyceride testing: The assay manufacturer Beckman Coulter advises "N-Acetyl Cysteine (NAC), when administered in therapeutic concentrations (for the treatment of acetaminophen overdose), has been determined to interfere with assays for cholesterol, uric acid" where "NAC interference may lead to falsely low results." According to Beckman Coulter, the NAC interference should be insignificant by 12 hours after completion of the initial loading dose of an IV infusion treatment regime consisting of an initial loading dose of 150 mg/kg administered over 1 hour, a second dose of 50 mg/kg administered over 4 hours and a third dose of 100 mg/kg administered over 16 hours. Comprehensive Metabolic Panel: Administration of STRENSIQ may interfere in certain assays and may falsely elevate values. For patients receiving STRENSIQ, consideration should be given to using alternate methods. TSH: Specimen collection after fluorescein dye angiography should be delayed for at least 3 days. For patients on hemodialysis, specimen collection should be delayed for 2 weeks after angiography. According to the assay manufacturer Siemens: samples containing fluorescein can produce falsely depressed values. |
| Preferred specimen(s) | 4.5 mL serum and 1 whole tube whole blood collected in an EDTA (lavender-top) tube and 10 mL random urine (no preservative) submitted in a plastic urine container |
| Minimum volume | 2.5 mL serum • 1 mL EDTA whole blood • 2 mL random urine |
| Collection instructions | Serum: Allow serum samples to clot completely before centrifugation. Random urine: Mix-well if aliquoting. Whole blood: Maintain specimen at room temperature. Do not refrigerate. If multiple draw, collect lavender-top tube last. Traumatic venipuncture tap can introduce thromboplastin and trap white blood cells and platelets. Refrigeration can precipitate fibrin and trap white blood cells and platelets. |
| Transport temperature | Serum: Refrigerated (cold packs) Whole blood and urine: Room temperature |
| Specimen stability | Serum Room temperature: 24 hours Refrigerated: 72 hours Frozen: Unacceptable Whole blood Room temperature: 48 hours Refrigerated: Unacceptable Frozen: Unacceptable Random urine Room temperature: 7 days Refrigerated: 7 days Frozen: 28 days |
| Reject criteria | Serum: Hemolysis • Grossly lipemic • Moderate to gross icterus • Anticoagulants other than heparin • Unspun serum separator tube (SST) Whole blood: Gross hemolysis • Clotted Random urine: Acid preserved urine |
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.
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