Mutated Citrullinated Vimentin (MCV) Antibody

Mutated Citrullinated Vimentin (MCV) Antibody

Test Code

13238
83520
13238
83520
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Mutated Citrullinated Vimentin (MCV) Antibody - Anti-mutated citrullinated vimentin (MCV) antibody is one of several specific anti-citrullinated protein antibodies which may be used as a second-line marker of rheumatoid arthritis (RA), in addition to rheumatoid factor and anti-cyclic citrullinated peptide (CCP). MCV antibody is less specific than CCP but has a slightly higher sensitivity and the addition of MCV to CCP adds 5-10% sensitivity for the diagnosis of RA. MCV antibody positivity is also associated with more severe disease and greater radiologic progression.

Test Resources

Clinical Focus

Autoimmune Rheumatic and Related Diseases

Test Summary

ANAlyzeR ANA, IFA with Reflex Titer/Pattern, Systemic Autoimmune Panel 1

Test Summary

Interstitial Lung Disease (ILD) Panel

Test Details

Methodology

Enzyme Linked Immunosorbent Assay (ELISA)

Reference Range(s)

<20 U/mL

Alternative Name(s)

anti-MCV,RA,Rheumatoid arthritis

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Enzyme Linked Immunosorbent Assay (ELISA)

Reference Range(s)

<20 U/mL

Alternative Name(s)

anti-MCV,RA,Rheumatoid arthritis
Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Collection Instructions

Draw whole blood using a red-top tube or serum separator tube (SST)

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
    Refrigerated: 14 days
    Frozen: 6 months

Setup Schedule

Service Area must be determined
1 mL serum
0.5 mL
Draw whole blood using a red-top tube or serum separator tube (SST)
Transport tube
Room temperature
Room temperature: 7 days
Refrigerated: 14 days
Frozen: 6 months
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.

Customize the test information for your Service Area