Hepatitis C Virus RNA, Quantitative Real-Time PCR with Reflex to Genotype

Hepatitis C Virus RNA, Quantitative Real-Time PCR with Reflex to Genotype

Test Code

11348
87522
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
11348
87522
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Hepatitis C Virus RNA, Quantitative Real-Time PCR with Reflex to Genotype - Useful in monitoring response to therapy and/or disease progression. Reportable range is 15 to 100,000,000 IU/mL (1.18-8.00 log IU/mL).

Test Resources

Test FAQ

HCV Genotyping

Test FAQ

Hepatitis C Virus Antibody and RNA Testing

Clinical Focus

Viral Hepatitis: Laboratory Support for Diagnosis and Management

Test Details

Includes

  • If Hepatitis C Viral RNA, Quantitative, Real-Time PCR is ≥2000 IU/mL, then Hepatitis C Virus RNA Genotype will be performed at an additional charge (CPT code(s): 87902).

Methodology

Real-Time Polymerase Chain Reaction

Reference Range(s)

HCV RNA, QN, Real-Time PCRNot detected (IU/mL)
HCV RNA, QN, Real-Time PCRNot detected (Log IU/mL)

Alternative Name(s)

Hepatitis C with Reflex

LOINC® Codes, Performing Laboratory

Service Area must be determined
If Hepatitis C Viral RNA, Quantitative, Real-Time PCR is ≥2000 IU/mL, then Hepatitis C Virus RNA Genotype will be performed at an additional charge (CPT code(s): 87902).

Methodology

Real-Time Polymerase Chain Reaction

Reference Range(s)

HCV RNA, QN, Real-Time PCRNot detected (IU/mL)
HCV RNA, QN, Real-Time PCRNot detected (Log IU/mL)

Alternative Name(s)

Hepatitis C with Reflex
Service Area must be determined

Preferred Specimen(s)

3 mL plasma collected in an EDTA (lavender-top) tube

Alternative Specimen(s)

Plasma collected in: PPT EDTA (white-top) tube • Serum

Minimum Volume

1.5 mL

Collection Instructions

Separate plasma from whole blood within 24 hours of collection by centrifugation. Transfer to a transport tube and refrigerate or freeze.

Serum is collected in a serum separator tube or red-top tube (no gel). Transfer to a transport tube and refrigerate or freeze.

Transport Container

Transport tube

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 72 hours
    Refrigerated: 14 days
    Frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Unspun PPT tube • Unspun serum separator tube (SST) • Unspun red-top tube (no gel) • Received room temperature • Specimens collected using heparin as anticoagulant

Setup Schedule

Service Area must be determined
3 mL plasma collected in an EDTA (lavender-top) tube
Plasma collected in: PPT EDTA (white-top) tube • Serum

1.5 mL

Separate plasma from whole blood within 24 hours of collection by centrifugation. Transfer to a transport tube and refrigerate or freeze.

Serum is collected in a serum separator tube or red-top tube (no gel). Transfer to a transport tube and refrigerate or freeze.
Transport tube
Refrigerated (cold packs)
Room temperature: 72 hours
Refrigerated: 14 days
Frozen: 30 days
Gross hemolysis • Grossly lipemic • Unspun PPT tube • Unspun serum separator tube (SST) • Unspun red-top tube (no gel) • Received room temperature • Specimens collected using heparin as anticoagulant
Service Area must be determined
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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