Thrombotic Marker Panel

Thrombotic Marker Panel

Test Code

11345
83520 (x2), 85362, 85379
11345
83520 (x2), 85362, 85379
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Thrombotic Marker Panel - When intravascular thrombosis is suspected in the absence of overt clinical symptoms, elevation in D-dimer, fibrin monomer, prothrombin fragment 1.2, or thrombin-antithrombin complex may be the only indicator of intravascular clot formation and generation of activated factor X. Marked elevation in only 1 or 2 of these markers should lead to further investigation of the site of the thrombosis (eg, early dissecting aortic aneurysm, anomalous arterial/venous fistula).

Test Resources

None found for this test
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Test Details

Includes

  • D-Dimer, Quantitative
  • Fibrin Monomer
  • Prothrombin Fragment 1.2
  • Thrombin- Antithrombin (TAT) Complex

Methodology

Enzyme Immunoassay (EIA) • Enzyme Linked Immunosorbent Assay (ELISA) • Hemagglutination (HA) • Immunoturbidimetric

Reference Range(s)

See individual tests

LOINC® Codes, Performing Laboratory

Service Area must be determined
D-Dimer, Quantitative
Fibrin Monomer
Prothrombin Fragment 1.2
Thrombin- Antithrombin (TAT) Complex

Methodology

Enzyme Immunoassay (EIA) • Enzyme Linked Immunosorbent Assay (ELISA) • Hemagglutination (HA) • Immunoturbidimetric

Reference Range(s)

See individual tests
Service Area must be determined

Preferred Specimen(s)

2 mL frozen platelet-poor plasma collected in each of three separate 3.2% sodium citrate (light blue-top) tubes

Minimum Volume

1 mL each specimen

Collection Instructions

Platelet-poor plasma: Centrifuge light blue-top tube for 15 minutes at approximately 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcL). Freeze immediately and ship on dry ice.

Transport Container

Transport tube(s)

Transport Temperature

Frozen

Specimen Stability

  • Room temperature: Unacceptable
  • Refrigerated: Unacceptable
  • Frozen: 21 days

Reject Criteria

Gross hemolysis • Received refrigerated • Received room temperature

Setup Schedule

Service Area must be determined
2 mL frozen platelet-poor plasma collected in each of three separate 3.2% sodium citrate (light blue-top) tubes
1 mL each specimen
Platelet-poor plasma: Centrifuge light blue-top tube for 15 minutes at approximately 1500 g within 60 minutes of collection. Using a plastic pipette, remove plasma, taking care to avoid the WBC/platelet buffy layer and place into a plastic vial. Centrifuge a second time and transfer platelet-poor plasma into a new plastic vial. Plasma must be free of platelets (<10,000/mcL). Freeze immediately and ship on dry ice.
Transport tube(s)
Frozen
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 21 days
Gross hemolysis • Received refrigerated • Received room temperature
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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