Citric Acid, 24-Hour Urine without Creatinine

Citric Acid, 24-Hour Urine without Creatinine

Test Code

11315
82507
11315
82507
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Citric Acid, 24-Hour Urine without Creatinine - This quantitative citric acid test, performed with a 24-hour urine specimen, may help assess the risk of calcium stone formation in the kidneys and inform patient management [1]. In general, 24-hour urine specimens are preferred to random urine specimens when measuring citric acid for diagnostic evaluation and monitoring of calcium nephrolithiasis [2].

Citrate inhibits calcium stone formation by binding and solubilizing calcium, which reduces supersaturation of calcium salts [1-2]. Approximately half of the patients with calcium stones have decreased urinary citrate levels [1]. Citrate is ...

Test Resources

None found for this test
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Test Details

Includes

  • CPT code 81050 may be added at an additional charge for volume measurement

Methodology

Spectrophotometry (SP)

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

100-1300 mg/24 h

Alternative Name(s)

Citrate

LOINC® Codes, Performing Laboratory

Service Area must be determined
CPT code 81050 may be added at an additional charge for volume measurement

Methodology

Spectrophotometry (SP)
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

100-1300 mg/24 h

Alternative Name(s)

Citrate
Service Area must be determined

Preferred Specimen(s)

10 mL aliquot of a 24-hour urine

Minimum Volume

1.5 mL

Collection Instructions

Do not include first morning specimen; collect all subsequent voidings. The last sample collected should be the first morning specimen voided the following morning at the same time as the previous morning's first voiding.
Specify 24-hour total volume on container and test requisition.

Transport Container

Plastic leak-proof urine container

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

  • Room temperature: 8 hours
  • Refrigerated: 30 days
  • Frozen: 60 days

Reject Criteria

Received room temperature • Acidified urine

Setup Schedule

Service Area must be determined
10 mL aliquot of a 24-hour urine
1.5 mL
Do not include first morning specimen; collect all subsequent voidings. The last sample collected should be the first morning specimen voided the following morning at the same time as the previous morning's first voiding.
Specify 24-hour total volume on container and test requisition.
Plastic leak-proof urine container
Refrigerated (cold packs)
Room temperature: 8 hours
Refrigerated: 30 days
Frozen: 60 days
Received room temperature • Acidified urine
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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