Pepsinogen II (PG II)

Pepsinogen II (PG II)

Test Code

11261
83519
11261
83519
Ordering Restrictions may apply. Please provide SERVICE AREA INFORMATION to find available tests you can order.
This test is not available in all locations. Please provide SERVICE AREA INFORMATION to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Pepsinogen II (PG II) - The Pepsinogens are gastric acid protease zymogens. They are divided into two distinct immunochemical groups. Pepsinogen I and II. Pepsinogen II is one of 4 aspartic proteinases: PG I, PG II, Cathepsin E and D. Pepsinogen II is produced primarily in the Oxyntic gland mucosa of the stomach, the gastric antrum and the duodenum. It is secreted mainly into the gastric lumen and into circulation. Pepsinogen II has little or no biological activity but in acid is converted to the active enzyme Pepsin which exhibits proteolytic actions. Unlike Pepsinogen I, Pepsinogen II ...

Test Resources

None found for this test
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Test Details

Patient Preparation

Patient should be fasting 10-12 hours prior to collection of specimen. Antacids or other medications affecting stomach acidity of gastrointestinal motility should be discontinued, if possible, for at least 48 hours prior to collection.

Methodology

Direct Enzyme Linked Immunosorbent Assay

Assay Category

This test was developed and its performance characteristics have been determined by Inter Science Institute. Values obtained with different methods, laboratories, or kits cannot be used interchangeably with the results on this report. The results cannot be interpreted as absolute evidence of the presence or absence of malignant disease.

This test is not available for New York patient testing.

Reference Range(s)

<22 ng/mL

LOINC® Codes, Performing Laboratory

Service Area must be determined
Patient should be fasting 10-12 hours prior to collection of specimen. Antacids or other medications affecting stomach acidity of gastrointestinal motility should be discontinued, if possible, for at least 48 hours prior to collection.

Methodology

Direct Enzyme Linked Immunosorbent Assay
This test was developed and its performance characteristics have been determined by Inter Science Institute. Values obtained with different methods, laboratories, or kits cannot be used interchangeably with the results on this report. The results cannot be interpreted as absolute evidence of the presence or absence of malignant disease.

This test is not available for New York patient testing.

Reference Range(s)

<22 ng/mL
Service Area must be determined

Preferred Specimen(s)

3 mL serum

Alternative Specimen(s)

EDTA (lavender-top)

Minimum Volume

1 mL

Collection Instructions

Specimen should be separated as soon as possible. Freeze immediately after separation.

Transport Container

Transport tube

Transport Temperature

Frozen

Specimen Stability

  • Room temperated: Unacceptable
  • Refrigerated: 72 hours
  • Frozen: 60 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Grossly icteric

Setup Schedule

Service Area must be determined
3 mL serum
EDTA (lavender-top)
1 mL
Specimen should be separated as soon as possible. Freeze immediately after separation.
Transport tube
Frozen
Room temperated: Unacceptable
Refrigerated: 72 hours
Frozen: 60 days
Gross hemolysis • Grossly lipemic • Grossly icteric
Service Area must be determined
Ordering Restrictions may apply. Please provide SERVICE AREA INFORMATION to find available tests you can order.
This test is not available in all locations. Please provide ACCOUNT INFORMATION NEEDED to confirm Test Code for the lab that services your account or to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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