Chymotrypsin, Stool

Test Code

11235

CPT Code(s)

84311

Test Code

11235

CPT Code(s)

84311

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Chymotrypsin, Stool - The diagnosis of chronic pancreatitis depends upon the demonstration of functional impairment of the pancreas. Impairment is determined by several means, two of which are:
1. Direct measurement of exocrine secretion into the duodenum after stimulation by a standard meal or after stimulation by intravenous secretin/pancreozymin.
2. The direct measurement of the activities of certain enzymes in feces. Chymotrypsin activity in stool, for example, has been shown to be lower than normal in patients with pancreatic exocrine insufficiency.

Test Resources

None found for this test
Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.

Test Details

Patient Preparation

Patients receiving pancreatic enzymes should discontinue taking the enzymes at least 5 days before the collection of the stool sample

Methodology

Enzymatic/Spectrophotometric

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

2.3-51.4 U/g

Alternative Name(s)

Fecal Chymotrypsin

LOINC® Codes, Performing Laboratory

Service Area must be determined

Patient Preparation

Patients receiving pancreatic enzymes should discontinue taking the enzymes at least 5 days before the collection of the stool sample

Methodology

Enzymatic/Spectrophotometric

Assay Category

Reference Range(s)

2.3-51.4 U/g

Alternative Name(s)

Fecal Chymotrypsin

LOINC® Codes, Performing Laboratory

Service Area must be determined

Preferred Specimen(s)

1 g random stool in a sterile leak-proof container

Minimum Volume

0.5 g

Transport Container

Sterile screw-cap vial

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria

Received room temperature

Setup Schedule

Service Area must be determined

Preferred Specimen(s)

1 g random stool in a sterile leak-proof container

Minimum Volume

0.5 g

Transport Container

Sterile screw-cap vial

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: Unacceptable
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria

Received room temperature

Setup Schedule

Service Area must be determined

Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.

In-home collection is not available in your area through Quest Mobile.

Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

The tests listed by specialty and category are a select group of tests offered. For a complete list of Quest Diagnostics tests, please adjust the filter options chosen, or refer to our Directory of Services.