Kappa/Lambda Light Chains, Free with Ratio

Kappa/Lambda Light Chains, Free with Ratio

Test Code

11234
83521 (x2)
11234
83521 (x2)
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Kappa/Lambda Light Chains, Free with Ratio - The Kappa/Lambda Light Chains, Free with Ratio, Serum test measures the amount of kappa and lambda free light chains (FLCs) in the blood and calculates the kappa to lambda ratio. It is used to assist in the diagnosis of plasma cell disorders, including multiple myeloma, primary amyloidosis, monoclonal gammopathy of unknown significance (MGUS), Waldenström's macroglobulinemia, and related disorders. It is also used to monitor disease activity and treatment.

Kappa and lambda light chains link with heavy chains to form immunoglobulins. In healthy individuals, most serum light chains are bound ...

Test Resources

None found for this test
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Test Details

Methodology

Immunoturbidimetric

Reference Range(s)

Kappa Light Chain, Free, Serum3.3-19.4 mg/L
Lambda Light Chain, Free, Serum5.7-26.3 mg/L
Kappa/Lambda Light Chains Free with Ratio, Serum0.26-1.65

Alternative Name(s)

Immunoglobulin Free Light Chains

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Immunoturbidimetric

Reference Range(s)

Kappa Light Chain, Free, Serum3.3-19.4 mg/L
Lambda Light Chain, Free, Serum5.7-26.3 mg/L
Kappa/Lambda Light Chains Free with Ratio, Serum0.26-1.65

Alternative Name(s)

Immunoglobulin Free Light Chains
Service Area must be determined

Preferred Specimen(s)

2 mL serum

Minimum Volume

1 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 72 hours
  • Refrigerated: 21 days
  • Frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Microbially contaminated • Heavy visible particulate

Setup Schedule

Service Area must be determined
2 mL serum
1 mL
Transport tube

Room temperature

Room temperature: 72 hours
Refrigerated: 21 days
Frozen: 30 days
Gross hemolysis • Grossly lipemic • Microbially contaminated • Heavy visible particulate
Service Area must be determined
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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