Kappa/Lambda Light Chains, Free with Ratio, Random Urine

Kappa/Lambda Light Chains, Free with Ratio, Random Urine

Test Code

11233
83521 (x2)
11233
83521 (x2)
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Kappa/Lambda Light Chains, Free with Ratio, Random Urine - Kappa/Lambda Light Chains, Free with Ratio, Urine by turbidimetry provides a sensitive detection and quantitation of free light chains (FLCs) in urine earlier than electrophoresis and immunofixation. Urinary FLCs (uFLCs) are known as Bence-Jones Proteins (BJP).
Abnormal levels of FLCs are commonly produced in a constellation of disorders referred as Plasma Cell Dyscrasia producing monoclonal gammopathies (MG), which constitutes neoplastic growth of plasma cell lines that secrete monoclonal proteins, either as intact immunoglobulins, or isolated light chains as in Light Chain Multiple Myeloma ...

Test Resources

None found for this test
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Test Details

Methodology

Immunoturbidimetry

Reference Range(s)

Kappa Light Chain, Free, Urine ≤32.90 mg/L
Lambda Light Chain, Free, Urine ≤3.79 mg/L
Kappa/Lambda, Free Ratio ≤8.69

Alternative Name(s)

Immunoglobulin Free Light Chains

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Immunoturbidimetry

Reference Range(s)

Kappa Light Chain, Free, Urine ≤32.90 mg/L
Lambda Light Chain, Free, Urine ≤3.79 mg/L
Kappa/Lambda, Free Ratio ≤8.69

Alternative Name(s)

Immunoglobulin Free Light Chains
Service Area must be determined

Preferred Specimen(s)

2 mL random

Alternative Specimen(s)

2 mL of 24-hour urine, no preservative

Minimum Volume

1 mL

Transport Container

Plastic urine container

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 7 days
  • Refrigerated: 21 days
  • Frozen: 30 days

Reject Criteria

Gross hemolysis • Microbial contamination

Setup Schedule

Service Area must be determined
2 mL random
2 mL of 24-hour urine, no preservative
1 mL
Plastic urine container
Room temperature
Room temperature: 7 days
Refrigerated: 21 days
Frozen: 30 days
Gross hemolysis • Microbial contamination
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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