Cyclic Citrullinated Peptide (CCP) Antibody (IgG)

Cyclic Citrullinated Peptide (CCP) Antibody (IgG)

Test Code

11173
86200
11173
86200
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

Cyclic Citrullinated Peptide (CCP) Antibody (IgG) - A synthetic circular peptide containing citrulline called CCP IgG (cyclic citrullinated peptide) has been found to be better at discriminating Rheumatoid Arthritis patients from patients with other diseases such as hepatitis C infection. Rheumatoid Arthritis Classification Criteria include CCP IgG Antibody, rheumatoid factor, C-reactive protein and erythrocyte sedimentation rate (ESR). Approximately 70% of patients with Rheumatoid Arthritis are positive for Anti-CCP IgG, while only about 2% of random blood donors and disease controls subjects are positive.

Test Resources

Clinical Focus

Idiopathic Inflammatory Myopathies: Laboratory Support for Diagnosis

Test Summary

ANAlyzeR ANA, IFA with Reflex Titer/Pattern, Systemic Autoimmune Panel 1

Test Summary

Interstitial Lung Disease (ILD) Panel

Test Details

Methodology

Immunoassay (IA)

Reference Range(s)

Negative <20 Units
Weak positive 20-39 Units
Moderate positive 40-59 Units
Strong positive >59 Units

Alternative Name(s)

Citrullinated Peptide (CCP) IgG,CCP,Anti-Cyclic Citrullinated Peptide (CCP) Antibody IgG

LOINC® Codes, Performing Laboratory

Service Area must be determined

Methodology

Immunoassay (IA)

Reference Range(s)

Negative <20 Units
Weak positive 20-39 Units
Moderate positive 40-59 Units
Strong positive >59 Units

Alternative Name(s)

Citrullinated Peptide (CCP) IgG,CCP,Anti-Cyclic Citrullinated Peptide (CCP) Antibody IgG
Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 4 days
  • Refrigerated: 7 days
  • Frozen: 30 days

Reject Criteria

Gross hemolysis • Grossly lipemic • Plasma

Setup Schedule

Service Area must be determined
1 mL serum
0.5 mL
Transport tube
Room temperature
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Gross hemolysis • Grossly lipemic • Plasma
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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