Angiotensin II Type 1 Receptor (AGTR1) Gene 1166A→C Polymorphism
Test Code
11118
81400
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Clinical Significance
Angiotensin II Type 1 Receptor (AGTR1) Gene 1166A→C Polymorphism - The ATR1 receptor gene polymorphism is associated with increased risk for hypertension and cardiovascular risk. Substantial increase in the c allele frequency was observed among patients with severe hypertension, particularly among individuals carrying DD ACE genotype.
Test Resources
None found for this test
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Please visit our Clinical Education Center to stay informed on any future publications, webinars, or other education opportunities.
Test Details
Methodology
Polymerase Chain Reaction (PCR) • Single Nucleotide Primer Extension
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Reference Range(s)
Negative
Preferred Specimen(s)
5 mL whole blood collected in an EDTA (lavender-top) tube
Alternative Specimen(s)
Whole blood collected in: ACD solution B (yellow-top) or sodium heparin (green-top) tube
Minimum Volume
3 mL
Collection Instructions
Whole blood: Normal phlebotomy procedure. Specimen stability is crucial. Store and ship at room temperature immediately. Do not freeze.
Transport Container
EDTA (lavender-top)
Transport Temperature
Room temperature
Specimen Stability
- Room temperature: 8 days
- Refrigerated: 8 days
- Frozen: Unacceptable
Reject Criteria
Call laboratory if blood samples received frozen
Setup Schedule
5 mL whole blood collected in an EDTA (lavender-top) tube
Whole blood collected in: ACD solution B (yellow-top) or sodium heparin (green-top) tube
3 mL
Whole blood: Normal phlebotomy procedure. Specimen stability is crucial. Store and ship at room temperature immediately. Do not freeze.
EDTA (lavender-top)
Room temperature
Room temperature: 8 days
Refrigerated: 8 days
Frozen: Unacceptable
Refrigerated: 8 days
Frozen: Unacceptable
Call laboratory if blood samples received frozen