Angiotensin II Type 1 Receptor (AGTR1) Gene 1166A→C Polymorphism

Angiotensin II Type 1 Receptor (AGTR1) Gene 1166A→C Polymorphism

Test Code

11118
81400
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
11118
81400
CPT Code is subject to a Medicare Limited Coverage Policy and may require a signed ABN when ordering.
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.

Clinical Significance

Angiotensin II Type 1 Receptor (AGTR1) Gene 1166A→C Polymorphism - The ATR1 receptor gene polymorphism is associated with increased risk for hypertension and cardiovascular risk. Substantial increase in the c allele frequency was observed among patients with severe hypertension, particularly among individuals carrying DD ACE genotype.

Test Resources

None found for this test
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Test Details

Methodology

Polymerase Chain Reaction (PCR) • Single Nucleotide Primer Extension

Assay Category

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

Negative

LOINC® Codes, Performing Laboratory

Methodology

Polymerase Chain Reaction (PCR) • Single Nucleotide Primer Extension
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Reference Range(s)

Negative

Preferred Specimen(s)

5 mL whole blood collected in an EDTA (lavender-top) tube

Alternative Specimen(s)

Whole blood collected in: ACD solution B (yellow-top) or sodium heparin (green-top) tube

Minimum Volume

3 mL

Collection Instructions

Whole blood: Normal phlebotomy procedure. Specimen stability is crucial. Store and ship at room temperature immediately. Do not freeze.

Transport Container

EDTA (lavender-top)

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 8 days
  • Refrigerated: 8 days
  • Frozen: Unacceptable

Reject Criteria

Call laboratory if blood samples received frozen

Setup Schedule

5 mL whole blood collected in an EDTA (lavender-top) tube
Whole blood collected in: ACD solution B (yellow-top) or sodium heparin (green-top) tube
3 mL
Whole blood: Normal phlebotomy procedure. Specimen stability is crucial. Store and ship at room temperature immediately. Do not freeze.
EDTA (lavender-top)
Room temperature
Room temperature: 8 days
Refrigerated: 8 days
Frozen: Unacceptable
Call laboratory if blood samples received frozen
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection is not available in your area through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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