ANA Multiplex, with Reflex to dsDNA

ANA Multiplex, with Reflex to dsDNA

Test Code

10547
86038
10547
86038
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.

Clinical Significance

ANA Multiplex, with Reflex to dsDNA - This multiplex immunoassay detects common antinuclear antibodies (ANAs) that are associated with autoimmune diseases. With a reflex to double-stranded DNA (dsDNA), this test may aid in the evaluation of systemic lupus erythematosus (SLE). Because of its limited sensitivity compared to that of ANA immunofluorescence-based tests, multiplex immunoassay is not the preferred assay for ANA testing [1].

This multiplex immunoassay identifies antibodies to dsDNA, chromatin, ribosomal protein, SSA, SSB, Sm, Sm/RNP, RNP, Scl-70, Jo-1, and centromere B. A positive result indicates the presence of at ...

Test Resources

None found for this test
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Test Details

Includes

  • If ANA Screen, Immunoassay is positive, then ds-DNA will be performed at an additional charge (CPT code(s): 86225)

Methodology

Immunoassay (IA)

Reference Range(s)

ANA Screen, ImmunoassayNegative

Alternative Name(s)

Systemic Lupus Erythematosus (SLE),Antinuclear Antibody Screen

LOINC® Codes, Performing Laboratory

Service Area must be determined
If ANA Screen, Immunoassay is positive, then ds-DNA will be performed at an additional charge (CPT code(s): 86225)

Methodology

Immunoassay (IA)

Reference Range(s)

ANA Screen, ImmunoassayNegative

Alternative Name(s)

Systemic Lupus Erythematosus (SLE),Antinuclear Antibody Screen
Service Area must be determined

Preferred Specimen(s)

1 mL serum

Minimum Volume

0.5 mL

Transport Container

Transport tube

Transport Temperature

Room temperature

Specimen Stability

  • Room temperature: 4 days
  • Refrigerated: 7 days
  • Frozen: 30 days
  •  

Reject Criteria

Gross hemolysis • Grossly lipemic • Grossly icteric

Setup Schedule

Service Area must be determined
1 mL serum
0.5 mL
Transport tube
Room temperature
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Gross hemolysis • Grossly lipemic • Grossly icteric
Service Area must be determined
Not offered in Quest Diagnostics Nichols Institute (IFD) – San Juan Capistrano. Please provide SERVICE AREA INFORMATION to find available tests you can order.
In-home collection may be available in your area for purchase through Quest Mobile.
Test Details

Clinical Significance

Test Resources

Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.

The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.

This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.

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