Enhanced Liver Fibrosis (ELF) Score
Test code
CPT code(s)*
Clinical significance
Test resources
Test FAQ
Details
Methodology
Chemiluminescent Immunoassay
Alternative name(s)
hyaluronic,P3NP,procollagen,metalloproteinase,hepatic,PIIINP,propeptide,NASH,NAFLD,Nonalcoholic,Fatty,Steatosis,Hepatitis,Steatohepatitis,TIMP
Specimen requirements | |
|---|---|
| Patient preparation | None Specified |
| Preferred specimen(s) | 1 mL serum |
| Minimum volume | 0.5 mL |
| Collection instructions | Spin sample within two hours after collection. Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation. Samples with fluorescein may cause falsely depressed results. Evidence suggests that patients undergoing retinal fluorescein angiography can retain amounts of fluorescein in the body for up to 72 hours post-treatment. |
| Transport container | Transport tube |
| Transport temperature | Refrigerated (cold packs) |
| Specimen stability | Room temperature: 48 hours Refrigerated: 7 days Frozen: 30 days |
| Reject criteria | Gross hemolysis |
Reference Range(s)
<9.80
ELF score ranges and associated risk of disease progression (development of cirrhosis or liver-related events):
| <9.80 | Lower |
| ≥9.80 - <11.30 | Mid |
| ≥11.30 | Higher |
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.
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