Micronutrients, Antioxidants Panel
Test code
CPT code(s)*
Test resources
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Details
Includes
10178 - Micronutrient, Coenzyme Q10 (CoQ10)
10179 - Micronutrient, Vitamin A (Retinol)
10181 - Micronutrient, Vitamin C
10183 - Micronutrient, Vitamin E (Alpha Tocopherol and Beta Gamma Tocopherol)
Methodology
Chromatography • Liquid Chromatography/Tandem Mass Spectrometry (LC/MS/MS)
Assay category
Micronutrient, Coenzyme Q10 (CoQ10): This test was developed and its performance characteristics determined by the Cleveland HeartLab, Inc. It has not been cleared or approved by the U.S. FDA. The Cleveland HeartLab, Inc. is regulated under Clinical Laboratory Improvement Amendments (CLIA) as qualified to perform high-complexity testing. This test is used for clinical purposes. It should not be regarded as investigational or for research.
Micronutrient, Vitamin A (Retinol), Vitamin C, and Vitamin E: This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Specimen requirements | |
|---|---|
| Patient preparation | Overnight fasting required. Avoid taking Coenzyme Q10 supplements the morning of the test. Refrain from eating fruits or taking vitamin C supplements 24 hours prior to collection. |
| Preferred specimen(s) | 3 mL serum - protected from light |
| Minimum volume | 1.5 mL |
| Collection instructions | Patients should be 18 years of age or greater. Gently invert specimen 5 times (DO NOT SHAKE!), allow to clot for 30-60 minutes at room temperature, centrifuge 10 minutes. Separate serum into 3 amber plastic transport tubes: 1 mL (0.5 mL min) for Vitamin A and E, protect from light, ship frozen (can be refrigerated). 1 mL (0.5 mL min) for Vitamin C, freeze immediately, protect from light, ship frozen. 1 mL (0.5 mL min) for CoQ10, protect from light, ship refrigerated. Do not ship on dry ice. Coenzyme Q10 must NOT be shipped on dry ice. Vitamin C must be shipped on dry ice. Additionally, for remote collection sites, or those with no access to ultra-low freezers or dry ice, it is recommended to schedule patient visits/draws after 12:00 p.m. local time and store the samples at -10° C to -30° C freezers (stable for 8 hours) until picked up by courier. Couriers should then transfer samples to -70° C storage (on dry ice) while enroute to the performing site location. |
| Transport container | Ship in amber tube or wrap specimen tubes in aluminum foil to protect from light |
| Transport temperature | Vitamins A and E, Coenzyme Q10: Refrigerated (cold packs) Vitamin C: Frozen -70° C |
| Specimen stability | Coenzyme Q10 (CoQ10) Room temperature: Unacceptable Refrigerated: 14 days Frozen: 6 weeks Vitamin A and Vitamin E Room temperature: 24 hours Refrigerated: 7 days Frozen: 28 days Vitamin C Room temperature: Unacceptable Refrigerated: Unacceptable Frozen -20° C: 8 hours Frozen -70° C: 35 days |
| Reject criteria | Hemolysis • Lipemia • Received room temperature • Not protected from light • Vitamin C received refrigerated |
Reference Range(s)
| Coenzyme Q10 (CoQ10) | >35 ug/mL |
Vitamin A (Retinol)
| 18-19 years | 26-72 mcg/dL |
| >19 years | 38-98 mcg/dL |
Vitamin C
| Male ≥18 years | 0.2-2.1 mg/dL |
| Female ≥18 years | 0.3-2.7 mg/dL |
Vitamin E
| Vitamin E, Alpha Tocopherol | ≥18 years | 5.7-19.9 mg/L |
| Vitamin E, Beta-Gamma Tocopherol | ≥18 years | <4.4 mg/L |
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.
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