Bladder Cancer, FISH
Test code
CPT code(s)*
Test resources
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Details
Methodology
Fluorescence in situ Hybridization (FISH)
Assay category
The analytical performance characteristics of this assay have been determined by Quest Diagnostics. The modifications have not been cleared or approved by the FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Alternative name(s)
Bladder Cancer Recurrence,Urovision,CEP 3, CEP 7, CEP 17, LSI 9p21 (p16),Uro-Vision,hematuria,Monitoring,Uro-Vysion,UroVysion™ Multicolor Probe
Specimen requirements | |
|---|---|
| Patient preparation | None Specified |
| Preferred specimen(s) | 50 mL voided urine collected in PreservCyt®, CytoLyt®, or ethanol 50% |
| Alternative specimen(s) | Bladder washing collected in a sterile leak-proof PreservCyt, CytoLyt, or ethanol 50% |
| Minimum volume | 33 mL |
| Collection instructions | Urine: A urine preservative transport kit, with handling instructions, is available upon request. Perform urine collection (50 mL) at the physician's office or Patient Service Center (PSC) in a sterile 100 mL urine specimen container. Mix voided urine with PreservCyt, CytoLyt, or ethanol 50% in a 1:1 solution. Alternatively, mix urine with preservative Carbowax™ (2% polyethylene glycol in 50% ethanol) 2:1 (v:v). Bladder washings: Perform bladder washing collection (50 mL) at the physician's office in a sterile 100 mL urine specimen container. Mix bladder washing with PreservCyt, CytoLyt, or ethanol 50% in a 1:1 solution. Alternatively, mix bladder washing with preservative Carbowax (2% polyethylene glycol in 50% ethanol) 2:1(v:v). It is recommended that specimens be processed within 72 hours of collection. Samples received without preservative will be assayed; any study under these conditions yielding insufficient cells or an abnormal result should have a follow-up study with urine in a preservative. Cold packs are recommended during transportation. If bladder washing is not shipped immediately after collection, refrigerate immediately (Do Not Freeze). Under no circumstances should bladder-washing specimens be stored or shipped at temperatures at or above 37° C. |
| Transport container | Plastic urine container |
| Transport temperature | Refrigerated (cold packs) |
| Specimen stability | Specimen viability decreases during transit. Send specimen to testing lab for viability determination. Do not freeze. Do not reject. |
Reference ranges are provided as general guidance only. To interpret test results use the reference range in the laboratory report.
*The CPT codes provided are based on AMA guidance and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payer being billed.
This material contains content from LOINC® (http://loinc.org). The LOINC Table, LOINC Table Core are copyright © 1995-2019, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee and is available at no cost under the license at http://loinc.org/license.
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